Fully automated preparation of [11C]choline and [18F]fluoromethylcholine using TracerLab synthesis modules and facilitated quality control using analytical HPLC
Authors:
- Brian G. HockleyBHBrian G. Hockley
- Raphaël HoareauRHRaphaël Hoareau
- Paul L. SchnauPSPaul L. Schnau
- Peter J.H. ScottPSPeter J.H. Scott
- 1 February 2011
- journal article
- research article
- Published by Elsevier in Applied Radiation and Isotopes
- Vol. 69 (2) , 403-409
Abstract
No abstract availableKeywords
Funding Information
- University of Michigan Cyclotron and Radiochemistry group gratefully acknowledges funding for this research from the Office of Biological and Environmental Research (BER) of the Office of Science (SC), U. S. Department of Energy (DE-FG02-08ER64645)
This publication has 11 references indexed in Scilit:
- A simple, versatile, low-cost and remotely operated apparatus for [11C]acetate, [11C]choline, [11C]methionine and [11C]PIB synthesisApplied Radiation and Isotopes, 2009
- Fully automated [18F]fluorocholine synthesis in the TracerLab MXFDG Coincidence synthesizerNuclear Medicine and Biology, 2008
- Simple automated system for simultaneous production of 11C-labeled tracers by solid supported methylationApplied Radiation and Isotopes, 2006
- Highly efficient automated synthesis of [11C]choline for multi dose utilizationApplied Radiation and Isotopes, 2004
- [18F]Fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholineApplied Radiation and Isotopes, 2002
- Review11C-Choline and 2-Deoxy-2-[18F]Fluoro-D-Glucose in Tumor Imaging with Positron Emission TomographyMolecular Imaging and Biology, 2002
- Improved method for the quality assurance of [C-11]cholineNuclear Medicine and Biology, 2002
- [11C]Methylation on a C18 Sep-Pak cartridge: a convenient way to produce [N-methyl-11C]cholineJournal of Labelled Compounds and Radiopharmaceuticals, 2000
- Automated synthesis of [11C]choline, a positron-emitting tracer for tumor imagingApplied Radiation and Isotopes, 1999
- A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparationsNuclear Medicine and Biology, 1997