Prophylactic Percutaneous Endoscopic Gastrostomy Tube Placement in Treatment of Head and Neck Cancer
- 28 April 2011
- journal article
- review article
- Published by Wiley in Journal of Parenteral and Enteral Nutrition
- Vol. 35 (3) , 365-374
Abstract
Background: Patients with head and neck cancers (HNCs) are at increased risk of experiencing malnutrition, which is associated with poor outcomes. Advances in the treatment of HNCs have resulted in improved outcomes that are associated with severe toxic oral side effects, placing patients at an even greater risk of malnutrition. Prophylactic placement of percutaneous endoscopic gastrostomy (PEG) tubes before treatment may be beneficial in patients with HNC, especially those undergoing more intense treatment regimens. PEG tube placement, however, is not without risks. Methods: A comprehensive review of the literature was conducted. Results: Systematic evidence assessing both the benefits and harm associated with prophylactic PEG tube placement in patients undergoing treatment for HNC is weak, and benefits and harm have not been established. Conclusions: More research is necessary to inform physician behavior on whether prophylactic PEG tube placement is warranted in the treatment of HNC.Keywords
Funding Information
- American Cancer Society
This publication has 115 references indexed in Scilit:
- Longitudinal oncology registry of head and neck carcinoma (LORHAN®): initial supportive care findingsSupportive Care in Cancer, 2009
- Malignant Seeding of Percutaneous Endoscopic Gastrostomy Tract in Patient With Head and Neck CancerThe American Journal of the Medical Sciences, 2008
- Long-Term Results of Concomitant Boost Radiation Plus Concurrent Cisplatin for Advanced Head and Neck Carcinomas: A Phase II Trial of the Radiation Therapy Oncology Group (RTOG 99-14)International Journal of Radiation Oncology - Biology - Physics (IJROBP), 2008
- Prophylactic gastrostomy placement and early tube feeding may limit loss of weight during chemoradiotherapy for advanced head and neck cancer, a preliminary studyClinical Otolaryngology, 2007
- Swallowing disorders in the first year after radiation and chemoradiationHead & Neck, 2007
- Effect of oral nutritional supplementation on weight loss and percutaneous endoscopic gastrostomy tube rates in patients treated with radiotherapy for oropharyngeal carcinomaSupportive Care in Cancer, 2007
- Functional outcomes after organ preservation treatment in head and neck cancer: a critical review of the literatureInternational Journal of Oral and Maxillofacial Surgery, 2006
- Predicting which patients can resume oral nutrition after percutaneous endoscopic gastrostomy tube placementAlimentary Pharmacology & Therapeutics, 2005
- Percutaneous radiological gastrostomy in patients with head and neck cancerEuropean Journal of Surgical Oncology, 2001
- The use of radiologically placed gastrostomy tubes in head and neck cancer patients receiving radiotherapyInternational Journal of Radiation Oncology - Biology - Physics (IJROBP), 1996