Reversal of progressive necrotizing vasculitis with intravenous pulse cyclophosphamide and methylprednisolone
Authors:
- 1 September 1988
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 31 (9) , 1194-1198
Abstract
We describe a patient with polyarteritis nodosa who, despite therapy with daily doses of oral prednisone and cyclophosphamide, developed acute renal failure. Renal histopathologic examination demonstrated crescentic glomerulonephritis. Treatment with intravenous pulse cyclophosphamide and methylprednisolone resulted in clinical improvement and significant recovery of renal function.Keywords
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