Supplementary Figure S2. STING-dependent regulation of proliferation is associated with perturbations of cell cycle. from STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability

Authors:
  • DRDiana Rose E. Ranoa
    Diana Rose E. Ranoa
  • RWRyan C. Widau
    Ryan C. Widau
  • SMStephen Mallon
    Stephen Mallon
  • APAkash D. Parekh
    Akash D. Parekh
  • CNClaudia M. Nicolae
    Claudia M. Nicolae
  • XHXiaona Huang
    Xiaona Huang
  • MBMichael J. Bolt
    Michael J. Bolt
  • AAAinhoa Arina
    Ainhoa Arina
  • RPRenate Parry
    Renate Parry
  • SKStephen J. Kron
    Stephen J. Kron
  • GMGeorge-Lucian Moldovan
    George-Lucian Moldovan
  • NKNikolai N. Khodarev
    Nikolai N. Khodarev
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Abstract
Cell cycle profile of pulse EdU-labeled (A) and chase EdU-labeled (B) WT and STING-/- MEFs at different time points post-IR treatment. Flow cytometry was used to measure the percent cell population in G1, S, and G2/M phase of single cells stained with AlexaFluor 647-conjugated anti-EdU (y-axis) and PI (x-axis).