Inhibition of P-glycoprotein-mediated multidrug resistance by unfractionated heparin: A new potential chemosensitizer for cancer therapy

Authors:
  • CFConcetta Di Febbo
    Concetta Di Febbo
  • GCGiuliano Ciofani
    Giuliano Ciofani
  • MNMarcello Di Nisio
    Marcello Di Nisio
  • GBGiovanna Baccante
    Giovanna Baccante
  • CICarmine Di Ilio
    Carmine Di Ilio
  • FCFranco Cuccurullo
    Franco Cuccurullo
  • EPEttore Porreca
    Ettore Porreca
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Abstract
Anticoagulant treatment with heparins is frequently used to prevent venous thromboembolism in cancer patient. In the present study, we investigared the ability of unfractionated heparin (UFH) to in...