An analogue of adenine that forms an “A:T” base pair of comparable stability to G:C
- 20 August 2004
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 19,p. 2208-2209
Abstract
The heterocyclic base 7-aminopropargyl-7-deaza-2,6-diaminopurine (D) has been incorporated into oligodeoxynucleotides. D:T has similar thermodynamic stability to G:C and is a stable analogue of A:T.Keywords
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