Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex
Authors:
- 15 August 2008
- journal article
- Published by Taylor & Francis in Cell Cycle
- Vol. 7 (16) , 2562-2569
Abstract
Ribonuclease HI (RNase H) is a member of the nucleotidyl-transferase superfamily and endo-nucleolytically cleaves the RNA portion in RNA/DNA hybrids and removes RNA primers from Okazaki fragments. ...Keywords
This publication has 39 references indexed in Scilit:
- Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse TranscriptionMolecular Cell, 2007
- Crystallization and preliminary X-ray analysis ofEscherichia coliRNase HI–dsRNA complexesActa Crystallographica Section F Structural Biology and Crystallization Communications, 2007
- Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent CatalysisCell, 2005
- Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 CatalysisJournal of Biological Chemistry, 2004
- Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA:DNAThe EMBO Journal, 2001
- Molecular diversities of RNases HJournal of Bioscience and Bioengineering, 1999
- How does RNase H recognize a DNA.RNA hybrid?Proceedings of the National Academy of Sciences, 1991
- Three-dimensional structure of ribonuclease H from E. coliNature, 1990
- Structure of a B-DNA dodecamer: conformation and dynamics.Proceedings of the National Academy of Sciences, 1981
- Crystal structure analysis of a complete turn of B-DNANature, 1980