DNA Methylation Leads to DNA Repair Gene Down-Regulation and Trinucleotide Repeat Expansion in Patient-Derived Huntington Disease Cells
- 1 July 2016
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 186 (7) , 1967-1976
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashionNeurology, 2012
- CAG‐repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approachesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2010
- Huntington's DiseaseSeminars in Neurology, 2007
- A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG lengthClinical Genetics, 2004
- Huntingtin aggregation and toxicity in Huntington's diseaseThe Lancet, 2003
- Mouse tissue culture models of unstable triplet repeats: in vitro selection for larger alleles, mutational expansion bias and tissue specificity, but no association with cell division ratesHuman Molecular Genetics, 2001
- Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?Human Molecular Genetics, 2000
- Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instabilityHuman Molecular Genetics, 2000
- Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and spermNature Genetics, 1994
- A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomesCell, 1993