Prevalence of Frailty and Associated Risk Factors in Geriatric Maintenance Hemodialysis Patients: A Cross-Sectional Study

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Abstract
Aim: Frailty is an important geriatric syndrome associated with adverse clinical outcomes. In chronic kidney disease, hemodialysis treatment prolongs survival; however, it cannot completely prevent the development of complications. This study aimed to determine the prevalence of frailty in geriatric patients receiving maintenance hemodialysis and to identify associated risk factors.Materials and Methods: This single-center, cross-sectional, observational study included a total of 419 geriatric individuals followed between April 15, 2024, and April 15, 2025. Of the participants, 136 were chronic kidney disease patients receiving maintenance hemodialysis, and 283 comprised a control group without a history of chronic kidney disease. Frailty was assessed using the Edmonton Frail Scale.Results: The prevalence of frailty was higher in the maintenance hemodialysis group than in the control group (58.1% vs. 39.2%, p=0.001). Among maintenance hemodialysis patients, frail individuals were older and had a higher comorbidity burden, longer duration of chronic kidney disease and hemodialysis, higher risk of malnutrition, and more frequent polypharmacy compared with non-frail individuals (all p
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  • There were no specific grants provided for this research from public, commercial, or nonprofit funding agencies.

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