Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors
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Open Access
- 1 January 2021
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 296, 100133
Abstract
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Funding Information
- UKRI | Medical Research Council (MR/R010676/1)
- Academy of Medical Sciences (N/A)
- Society for Endocrinology (N/A)
- British Society for Neuroendocrinology (N/A)
- European Association for the Study of Diabetes (N/A)
- UKRI | Engineering and Physical Sciences Research Council (N/A)
- Diabetes UK (N/A)
- Diabetes UK (BDA/11/0004210 BDA/15/0005275 BDA 16/0005485)
- Wellcome (212625/Z/18/Z)
- UKRI | Medical Research Council (MR/R022259/1 DIVA MR/L02036X/1)
- Innovative Medicines Initiative (RHAPSODY grant No 115881)
- FP7 Health (2009-241592 EuroCHIP)
- Fondation de la Recherche Médicale (Equipe FRM DEQ20130326503 EQU201903008055)
- Agence Nationale de la Recherche (ANR-2011-BSV1-012-01 “MLT2D” and ANR-2011-META “MELA-BETES ANR-19-CE16-0025-01 ANR-15-CE14-0025-02)
- Institut National de la Santé et de la Recherche Médicale (N/A)
- Centre National de la Recherche Scientifique (N/A)
- Japan Agency for Medical Research and Development (PRIME JP19gm5910013 LEAP JP19gm0010004)
This publication has 83 references indexed in Scilit:
- Automated method for the rapid and precise estimation of adherent cell culture characteristics from phase contrast microscopy imagesBiotechnology and Bioengineering, 2013
- A Simple Method for Quantifying Functional Selectivity and Agonist BiasACS Chemical Neuroscience, 2012
- Spatiotemporally Regulated Protein Kinase A Activity Is a Critical Regulator of Growth Factor-Stimulated Extracellular Signal-Regulated Kinase Signaling in PC12 CellsMolecular and Cellular Biology, 2011
- Metabolism and Excretion of the Once-Daily Human Glucagon-Like Peptide-1 Analog Liraglutide in Healthy Male Subjects and Its In Vitro Degradation by Dipeptidyl Peptidase IV and Neutral EndopeptidaseDrug Metabolism and Disposition, 2010
- Computer Control of Microscopes Using µManagerCurrent Protocols in Molecular Biology, 2010
- GLP-1 Mediates Antiapoptotic Effect by Phosphorylating Bad through a β-Arrestin 1-mediated ERK1/2 Activation in Pancreatic β-CellsJournal of Biological Chemistry, 2010
- β-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic β cellsProceedings of the National Academy of Sciences, 2008
- Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP productionEuropean Journal of Medicinal Chemistry, 2004
- The Positive Charge of the Imidazole Side Chain of Histidine7 Is Crucial for GLP-1 Action.Endocrine Journal, 1997
- Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serumEuropean Journal of Biochemistry, 1993