Absent in melanoma 2 regulates tumor cell proliferation in glioblastoma multiforme
- 6 July 2019
- journal article
- research article
- Published by Springer Nature in Journal of Neuro-Oncology
- Vol. 144 (2) , 265-273
Abstract
Inflammation is a key aspect of glioblastoma multiforme (GBM) although it remains unclear how it contributes to GBM pathogenesis. Inflammasomes are intracellular multi-protein complexes that are involved in innate immunity and are activated by cellular stress, principally in macrophages. This study examined the expression of inflammasome-associated genes in GBM, particularly absent in melanoma 2 (AIM2).Keywords
Funding Information
- University Hospital Foundation
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