Uterine Sarcomas: Then and Now
Authors:
- 1 July 2012
- journal article
- review article
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 199 (1) , 213-223
Abstract
OBJECTIVE. The purpose of this article is to provide an updated review of uterine sarcomas. The traditionally described neoplasms are reviewed as well as several recently characterized entities in terms of their imaging and clinical aspects. We attempt to provide a longitudinal imaging overview, from initial presentation to follow-up. Imaging features are also described of response to traditional therapeutic agents and newer targeted agents. CONCLUSION. A greater understanding of the pathogenesis has improved our ability to image and treat uterine sarcomas, both at initial staging and on follow-up. Targeted therapy is assuming an increasingly important role in the management of these lesions. It is imperative for radiologists to be aware of response characteristics and potential complications of these agents as well as conventional chemotherapeutic agents.Keywords
This publication has 66 references indexed in Scilit:
- Aromatase inhibitor-associated bone and musculoskeletal effects: new evidence defining etiology and strategies for managementBreast Cancer Research, 2011
- Trabectedin: Safety and Efficacy in the Treatment of Advanced SarcomaClinical Medicine Insights: Oncology, 2011
- The impact of multi-modal therapy on survival for uterine carcinosarcomasGynecologic Oncology, 2010
- Uterine Leiomyosarcoma : 14-year Two-center Experience of 31 CasesCancer Research and Treatment, 2009
- Endometrial stromal sarcoma: a population-based analysisBritish Journal of Cancer, 2008
- Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma: A Gynecologic Oncology Group phase II trialGynecologic Oncology, 2008
- Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasmInternational Seminars in Surgical Oncology, 2008
- Endometrial Stromal Sarcomas: A Retrospective Analysis of 28 Patients, Single Center Experience for 20 YearsCancer Research and Treatment, 2008
- Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcomaGynecologic Oncology, 2007
- Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas?Journal of Clinical Pathology, 2002