Ketone monoester intake affects the ventilatory response to O 2 and CO 2 in healthy individuals at high altitude
Open Access
- 1 November 2026
- journal article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 331 (5) , R671-R681
Abstract
Ketone ester (KE) intake attenuates the ventilatory response to O 2 and CO 2 after 20 h at 3,375 m, and this most likely results from hyperventilation induced by KE intake, rather than reflecting altered ventilatory reactivity to O 2 and/or CO 2 per se. Conversely, despite accentuated acid-base disruptions, ketosis did not affect cerebrovascular parameters.Keywords
Funding Information
- Fonds Wetenschappelijk Onderzoek (G073522N)
- Fonds Wetenschappelijk Onderzoek (12B0E24N)
- The Slovenian Research and Innovation Agency (N5-0247)
- The Slovenian Research and Innovation Agency (J5-50180)
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