Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control
Open Access
- 1 March 2019
- journal article
- research article
- Published by Elsevier in Cell Reports
- Vol. 26 (10) , 2779-2791.e5
Abstract
No abstract availableKeywords
Funding Information
- Wellcome Trust Investigator award (107791/Z/15/Z)
- Lister Institute Research Fellowship
- MRC
- Wellcome Trust (095518/Z/11/Z)
This publication has 58 references indexed in Scilit:
- TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusionsGenome Biology, 2013
- Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosomeProceedings of the National Academy of Sciences, 2011
- iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolutionNature Structural & Molecular Biology, 2010
- The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3LThe EMBO Journal, 2010
- BEDTools: a flexible suite of utilities for comparing genomic featuresBioinformatics, 2010
- The Sequence Alignment/Map format and SAMtoolsBioinformatics, 2009
- The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosomeNucleic Acids Research, 2009
- C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processingNucleic Acids Research, 2007
- Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genomeNature Genetics, 2007
- Cryptic Pol II Transcripts Are Degraded by a Nuclear Quality Control Pathway Involving a New Poly(A) PolymeraseCell, 2005