Early Insulin Therapy in Very-Low-Birth-Weight Infants
Authors:
- Sophie VanhaesebrouckSVSophie Vanhaesebrouck
- Amanda L. Ogilvy-StuartAOAmanda L. Ogilvy-Stuart
- Christine VanholeCVChristine Vanhole
- Christopher R. PalmerCPChristopher R. Palmer
- Mirjam van WeissenbruchMWMirjam van Weissenbruch
- Paula MidgleyPMPaula Midgley
- Michael ThompsonMTMichael Thompson
- Marta ThioMTMarta Thio
- Luc CornetteLCLuc Cornette
- Iviano OssuettaIOIviano Ossuetta
- Isabel IglesiasIIIsabel Iglesias
Open Access
- 30 October 2008
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 359 (18) , 1873-1884
Abstract
Studies involving adults and children being treated in intensive care units indicate that insulin therapy and glucose control may influence survival. Hyperglycemia in very-low-birth-weight infants is also associated with morbidity and mortality. This international randomized, controlled trial aimed to determine whether early insulin replacement reduced hyperglycemia and affected outcomes in such neonates.Keywords
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