Copper‐Catalyzed Conjugate Addition of Trimethylaluminium to α,β‐Unsaturated Ketones
Authors:
- 1 August 1994
- journal article
- research article
- Published by Wiley in European Journal of Inorganic Chemistry
- Vol. 127 (8) , 1489-1493
Abstract
The conjugate methylation of α,β‐unsaturated ketones with trimethylaluminium occurs smoothly in a very simple procedure under the catalytic effect of Cu1 salts. Scope and limitations of this process as well as the influence of solvent and catalyst on the kinetics were studied. In addition, the effect of chlorotrimethylsilane as an additive was investigated. Attack on the carbonyl group in 1,2‐fashion could not be observed under the reaction conditions.Keywords
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