Intratumoral T cell activation kills tumors regardless of T cell specificity
- 8 September 2026
- journal article
- research article
- Published by Springer Nature in Nature Immunology
- Vol. 27 (10) , 2134-2142
Abstract
No abstract availableKeywords
Funding Information
- National Cancer Institute (R01CA238439)
- National Cancer Institute (F30CA253992)
- National Cancer Institute (P30-CA014051)
- National Institute of Allergy and Infectious Diseases (R01AI146032)
- National Institute of Allergy and Infectious Diseases (R01AI084913)
- National Institute of Allergy and Infectious Diseases (F30AI181450)
- St. Jude Children's Research Hospital (GR1001820)
This publication has 33 references indexed in Scilit:
- Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathwayImmunity, 2022
- Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sexCell Reports, 2021
- Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock SyndromesCell, 2021
- Oxidative Stress in CancerCancer Cell, 2020
- Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor ImmunityCell Reports, 2018
- Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer TherapeuticsCancer Cell, 2017
- RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A VirusCell Host & Microbe, 2016
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and ImmunityCell Reports, 2015
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic TumorsImmunity, 2014
- Hallmarks of Cancer: The Next GenerationCell, 2011