The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence
Open Access
- 26 January 2012
- journal article
- Published by Wiley in ISRN Psychiatry
- Vol. 2012, 1-6
Abstract
The presence of depression in alcohol-dependent persons is likely to influence treatment process and outcomes. Identification of depression is important though not every depressed alcohol-dependent person requires treatment with antidepressants. Understanding the association between depression and alcohol dependence is essential for proper management of alcohol dependence. Objectives. To determine the prevalence of depression among alcohol-dependent persons before and after alcohol detoxification and rehabilitation. Design. Clinical trial with pre-/postmeasurements. Method. The CIDI and WHO-ASSIST were administered to 188 alcohol-dependent persons at intake and after six months. A researcher-designed sociodemographic questionnaire was also administered at intake. Results. The prevalence of depression among alcohol-dependent persons is high (63.8%) with a significant association between depression and the mean AUDIT score. At posttest, depressed participants had a statistically significant craving for alcohol. Conclusion. Alcohol dependence is associated with major depression.Keywords
This publication has 48 references indexed in Scilit:
- Genome-wide linkage scans for major depression in individuals with alcohol dependenceJournal of Psychiatric Research, 2010
- Mechanisms of behavior change in alcoholics anonymous: does Alcoholics Anonymous lead to better alcohol use outcomes by reducing depression symptoms?Addiction, 2010
- CLOCK is suggested to associate with comorbid alcohol use and depressive disordersJournal of Circadian Rhythms, 2010
- Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorderAddictive Behaviors, 2009
- THE EFFECT OF BRIEF ALCOHOL INTERVENTION ON POSTPARTUM DEPRESSIONMCN: The American Journal of Maternal/Child Nursing, 2009
- Mood‐Related Drinking Motives Mediate the Familial Association Between Major Depression and Alcohol DependenceAlcohol, Clinical and Experimental Research, 2009
- Alcohol intoxication and mental health among adolescents – a population review of 8983 young people, 13–19 years in North-Trøndelag, Norway: the Young-HUNT StudyChild and Adolescent Psychiatry and Mental Health, 2009
- Longitudinal Associations Between Alcohol Problems and Depressive Symptoms: Early Adolescence Through Early AdulthoodAlcohol, Clinical and Experimental Research, 2008
- Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approachBioData Mining, 2008
- Association of a D2S2944 allele with depression specifically among those with substance abuse or antisocial personalityDrug and Alcohol Dependence, 2006