Acute therapy with hemopexin (CSL889) resolves LPS-induced lung vaso-occlusion in sickle mice
Authors:
- Rikesh K. DubeyRDRikesh K. Dubey
- Ravi VatsRVRavi Vats
- Thomas GentinettaTGThomas Gentinetta
- Tomasz W. KaminskiTKTomasz W. Kaminski
- ManikantaMAManikanta
- Omika KatochOKOmika Katoch
- Tirthadipa Pradhan-SunddTPTirthadipa Pradhan-Sundd
- Jesus TejeroJTJesus Tejero
- Brandon GreeneBGBrandon Greene
- Gregory J. KatoGKGregory J. Kato
- Paolo RossatoPRPaolo Rossato
- Gerald HoebarthGHGerald Hoebarth
Open Access
- 13 July 2026
- journal article
- Published by Elsevier in Blood Vessels, Thrombosis & Hemostasis
- Vol. 3 (3)
Abstract
No abstract availableFunding Information
- CSL Behring
- National Heart, Lung, and Blood Institute
This publication has 21 references indexed in Scilit:
- CD39 polymorphism enables lung thrombosis in sickle cell diseaseNature Communications, 2026
- Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000–2021: a systematic analysis from the Global Burden of Disease Study 2021The Lancet Haematology, 2023
- Pathophysiology of Sickle Cell DiseaseAnnual Review of Pathology: Mechanisms of Disease, 2019
- Crizanlizumab for the Prevention of Pain Crises in Sickle Cell DiseaseNew England Journal of Medicine, 2017
- Pulmonary platelet thrombi and vascular pathology in acute chest syndrome in patients with sickle cell diseaseAmerican Journal of Hematology, 2015
- Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistanceThe Journal of Physiology, 2015
- Low NO Concentration Dependence of Reductive Nitrosylation Reaction of HemoglobinJournal of Biological Chemistry, 2012
- P-Selectin–Mediated Platelet-Neutrophil Aggregate Formation Activates Neutrophils in Mouse and Human Sickle Cell DiseaseArteriosclerosis, Thrombosis, and Vascular Biology, 2010
- Sickle-cell diseaseThe Lancet, 2010
- Transport of heme by hemopexin to the liver: Evidence for receptor-mediated uptakeBiochemical and Biophysical Research Communications, 1978