Selective Reduction of Phosphatides with Lithium Aluminum Hydride. I. Ovolecithin
Authors:
- 1 February 1960
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 33 (2) , 144-149
Abstract
The optimum conditions for cleavage of the fatty acid ester linkages in the lecithin molecule were found to be 20 min. at 10°C with the use of two moles of lithium aluminum hydride per mole of lecithin. The product formed under these conditions was identified to be l-α-glycerylphosphorylcholine when ovolecithin which was shown to be l-α-lecithin was used. Discussion has been presented as to two mechanisms possibly participating in the cleavage of glycerylphosphorylcholine, one involving a complex formation with the phosphoryl group and the other with the cationic nitrogen atom of the choline base.Keywords
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