A Candidate Bacterial-Type Amino Acid Decarboxylase Is Essential for Male Gamete Exflagellation and Mosquito Transmission of the Malaria Parasite

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Abstract
A frequent side effect of chemotherapy against malaria parasite blood infections is a dramatic induction of the sexual blood stages, thereby enhancing the risk of future malaria transmissions. The polyamine biosynthesis pathway has been suggested as a candidate target for transmission-blocking anti-malarial drug development.
Funding Information
  • TÜBİTAK (119Z409)
  • HHS | NIH | National Institute of Allergy and Infectious Diseases (1R21AI111058-01A1)

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