Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer
Open Access
- 1 August 2014
- journal article
- research article
- Published by Elsevier in Gastroenterology
- Vol. 147 (2) , 418-429.e8
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
- Project 211 (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
- International Science and Technology Cooperation Programme (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
- National Institutes of Health (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
- National Cancer Institute (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
- Burroughs Wellcome Fund (5P50CA150964, 81201920, B12003, 2011DFA32570, K07CA122451, P01CA077852, P30CA15704, P30CA68485, P50CA95103, R01CA121060, RO1CA115513, U54CA143862, UO1CA152756)
This publication has 52 references indexed in Scilit:
- Comprehensive molecular characterization of human colon and rectal cancerNature, 2012
- Epigenetics and colorectal cancerNature Reviews Gastroenterology & Hepatology, 2011
- Conserved role of intragenic DNA methylation in regulating alternative promotersNature, 2010
- Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblastsNature Genetics, 2009
- The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shoresNature Genetics, 2009
- Genomic and Epigenetic Instability in Colorectal Cancer PathogenesisGastroenterology, 2008
- A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingNature Genetics, 2007
- CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerNature Genetics, 2006
- CpG island methylator phenotype in cancerNature Reviews Cancer, 2004
- Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colonNature Genetics, 1994