Development of Noonan syndrome by deregulation of allosteric SOS autoactivation

This publication has 31 references indexed in Scilit:

• SOS1 mutations in Noonan syndrome: molecular spectrum, structural insights on pathogenic effects, and genotype-phenotype correlations
  Human Mutation, 2011
• Allosteric gating of Son of sevenless activity by the histone domain
  Proceedings of the National Academy of Sciences, 2010
• A restricted spectrum of NRAS mutations causes Noonan syndrome
  Nature Genetics, 2009
• Membrane-dependent signal integration by the Ras activator Son of sevenless
  Nature Structural & Molecular Biology, 2008
• GEFs and GAPs: Critical Elements in the Control of Small G Proteins
  Cell, 2007
• Unusual Interplay of Two Types of Ras Activators, RasGRP and SOS, Establishes Sensitive and Robust Ras Activation in Lymphocytes
  Molecular and Cellular Biology, 2007
• Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome
  Nature Genetics, 2006
• Germline gain-of-function mutations in SOS1 cause Noonan syndrome
  Nature Genetics, 2006
• Germline Missense Mutations Affecting KRAS Isoform B Are Associated with a Severe Noonan Syndrome Phenotype
  The American Journal of Human Genetics, 2006
• Germline KRAS mutations cause Noonan syndrome
  Nature Genetics, 2006