High susceptibility to the novel antimicrobial zoliflodacin among Neisseria gonorrhoeae isolates in eight WHO Enhanced Gonococcal Antimicrobial Surveillance Programme countries in three WHO regions, 2021-2024
Authors:
Open Access
- 11 March 2025
- journal article
- Published by Elsevier in IJID Regions
- Vol. 15, 100624
Abstract
No abstract availableKeywords
Funding Information
- World Health Organization
- Örebro University Hospital
This publication has 29 references indexed in Scilit:
- Antimicrobial-resistant Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance studyThe Lancet Microbe, 2024
- Antimicrobial treatment and resistance in sexually transmitted bacterial infectionsNature Reviews Microbiology, 2024
- High prevalence of ceftriaxone-resistant and XDR Neisseria gonorrhoeae in several cities of Cambodia, 2022–23: WHO Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP)JAC-Antimicrobial Resistance, 2024
- Neisseria gonorrhoeae antimicrobial susceptibility trends in Bangkok, Thailand, 2015–21: Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP)JAC-Antimicrobial Resistance, 2023
- Global Transmission of the penA Allele 60.001–Containing High-Level Ceftriaxone-Resistant Gonococcal FC428 Clone and Antimicrobial Therapy of Associated Cases: A ReviewInfectious Microbes and Diseases, 2023
- GyrB in silico mining in 27 151 global gonococcal genomes from 1928–2021 combined with zoliflodacin in vitro testing of 71 international gonococcal isolates with different GyrB, ParC and ParE substitutions confirms high susceptibilityJournal of Antimicrobial Chemotherapy, 2022
- WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational studyThe Lancet Microbe, 2021
- High susceptibility to zoliflodacin and conserved target (GyrB) for zoliflodacin among 1209 consecutive clinicalNeisseria gonorrhoeaeisolates from 25 European countries, 2018Journal of Antimicrobial Chemotherapy, 2021
- Zoliflodacin: An Oral Spiropyrimidinetrione Antibiotic for the Treatment of Neisseria gonorrheae, Including Multi-Drug-Resistant IsolatesACS Infectious Diseases, 2020
- World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international collaborative actions and research effortsSexual Health, 2019