Characterization of Cytochalasins and Steroids From the Ascomycete Daldinia concentrica and Their Cytotoxicity
Open Access
- 20 May 2019
- journal article
- research article
- Published by SAGE Publications in Natural Product Communications
- Vol. 14 (5)
Abstract
One new cytochalasin daldinin (1), 2 known cytochalasins 2 and 3, along with 2 steroids 4 and 5, were characterized from the methanol extracts of the fruiting bodies of Daldinia concentrica. The structure of new compound 1 was elucidated using a combination of 1- and 2-dimensional nuclear magnetic resonance spectroscopic and high-resolution electrospray ionization mass spectrometric analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumor cell lines and the tested compounds demonstrated moderate-to-weak cytotoxicity.Keywords
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