A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl

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Abstract
A new iridoid glycoside, namely 8-O-(threo-2, 3-dihydroxyl-3-phenyl-propionoyl)-harpagide (1), along with a new cinnamoyl glycoside named as cis-sibirioside A (2), were isolated from Scrophularia ningpoensis Hemsl. Their chemical structures were completely established by spectroscopic methods and comparison with related literatures. Compound 1 exhibited moderate antifouling effect against the settlement of Balanus amphitrite larvae with IC50 being 13.5 μg/mL and LC50 > 25 μg/mL.
Funding Information
  • Research Foundation from Department of Education of Jiangxi Province (460911)
  • Hong Kong Research Grants Council Theme-Based Research Scheme (T13-607/12R)
  • National Natural Science Fund of China (41506156)
  • Natural Science Fund of Guangdong Province (2016A030310095)

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