Chirality-dependent halogen bonds in axially chiral quinazolin-4-one derivatives bearing ortho-halophenyl groups
- 16 May 2019
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in CrystEngComm
- Vol. 21 (22) , 3385-3389
Abstract
In the crystals prepared from racemic axially chiral 3-(ortho-halophenyl)-2-methylquinazolin-4-one derivatives, the formation of intermolecular halogen bonding (CO⋯X) between the carbonyl oxygen and ortho-halogen atom (X = Cl, Br, I) was found, while in the crystals prepared from their optically pure forms, such halogen bonding was not detected.Keywords
Funding Information
- Japan Society for the Promotion of Science (KAKENNHI C17K08220)
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