Left Atrial and Left Atrial Appendage 4D Blood Flow Dynamics in Atrial Fibrillation

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Abstract
Background—: Atrial 4D flow magnetic resonance imaging was used for the characterization of left atrial (LA) and left atrial appendage (LAA) flow dynamics in patients with atrial fibrillation (AF). Methods and Results—: 4D flow magnetic resonance imaging measured in vivo 3D blood flow velocities in 60 AF patients and 15 controls. Anatomic maps of LA and LAA stasis and velocity were calculated to quantify atrial peak velocity, mean velocity, and stasis (velocities P P 2 DS 2 -VASc score was associated with significantly ( P P r =0.41) and stasis ( r =−0.39). Conclusions—: AF resulted in overall impaired but individually variable flow dynamics in both the LA and LAA. AF patients demonstrated atrial flow in the normal range, despite elevated CHA 2 DS 2 -VASc score.

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