Supplementary Figure S3 from A Novel CDK12 Inhibitor Induces Homologous Recombination Deficiency to Enhance PARP Inhibitor Efficacy in Uterine Serous Carcinoma

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Abstract
Supplementary Figure S3 shows the generation and characterization of CDK12 knockdown cell lines using short hairpin RNA (shRNA) in human uterine serous carcinoma and mouse endometrial carcinoma models, including validation of CDK12 protein reduction and effects on cell proliferation.