Characterization of adeno-associated virus capsid proteins using denaturing size-exclusion chromatography coupled with mass spectrometry
Open Access
- 16 October 2024
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical and Biomedical Analysis
- Vol. 253, 116524
Abstract
No abstract availableKeywords
Funding Information
- Regeneron Pharmaceuticals
This publication has 32 references indexed in Scilit:
- Mass spectrometry in gene therapy: Challenges and opportunities for AAV analysisDrug Discovery Today, 2022
- The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotidesJournal of Chromatography A, 2022
- Investigating the secondary interactions of packing materials for size-exclusion chromatography of therapeutic proteinsJournal of Chromatography A, 2022
- Impact of Nonspecific Adsorption to Metal Surfaces in Ion Pair-RP LC-MS Impurity Analysis of OligonucleotidesJournal of Pharmaceutical and Biomedical Analysis, 2022
- Characterization of Adeno-Associated Virus Capsid Proteins Using Hydrophilic Interaction Chromatography Coupled with Mass SpectrometryJournal of Pharmaceutical and Biomedical Analysis, 2020
- Thermal Stability as a Determinant of AAV Serotype IdentityMolecular Therapy - Methods & Clinical Development, 2017
- Theory and practice of size exclusion chromatography for the analysis of protein aggregatesJournal of Pharmaceutical and Biomedical Analysis, 2014
- The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticalsJournal of Pharmaceutical Sciences, 2010
- Analysis of reduced monoclonal antibodies using size exclusion chromatography coupled with mass spectrometryJournal of the American Society for Mass Spectrometry, 2009
- Effect of eluent on the ionization process in liquid chromatography–mass spectrometryJournal of Chromatography A, 2009