Prognostic significance of serum B-lymphocyte stimulator level in Hodgkin's lymphoma
Authors:
- Y. OkiYOY. Oki
- G. V. GeorgakisGGG. V. Georgakis
- T.-S. MigoneTMT.-S. Migone
- L. W. KwakLKL. W. Kwak
- A. YounesAYA. Younes
- 1 February 2007
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 92 (2) , 269-270
Abstract
B-lymphocyte stimulator (BLyS) plays a critical role in the survival of B-lymphocytes. In 50 patients with Hodgkin’s lymphoma BLyS levels were higher in newly diagnosed patients (median 2.0 ng/mL, range p=0.01) and shorter progression-free survival (log-rank p=0.029, 2-year rate 64% vs 100%). Serum BLyS levels may have prognostic significance in Hodgkin’s lymphoma.Keywords
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