Iain A. Wilson
Research Subjects
Iain A. Wilson has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Carlo Colantuoni
Department of Biostatistics, The Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
1 shared publication Heikki Tanila
Department of Neurobiology, A.I.Virtanen Institute, University of Kuopio 70211, Finland
1 shared publication- Heikki Tanila
Department of Neuroscience and Neurology, University and University Hospital of Kuopio, Kuopio, Finland
1 shared publication Howard Eichenbaum
Department of Psychology, Boston University, Boston, MA 02215, USA
1 shared publication- Howard Eichenbaum
Boston University
1 shared publication Michela Gallagher
Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
1 shared publication
Latest Publications
- 1 December 2006
- Published by Elsevier in Trends in Neurosciences
- Vol. 29 (12) , 662-670
Neurocognitive aging: prior memories hinder new hippocampal encoding
- 1 December 2006
- Published by Elsevier in Trends in Neurosciences
- Vol. 29 (12) , 662-670
Neurocognitive aging: prior memories hinder new hippocampal encoding
- 25 November 2006
- Published by Springer Nature in AGE
- Vol. 28 (3) , 221-233
Individual differences in neurocognitive aging of the medial temporal lobe
A wide spectrum of outcomes in the cognitive effects of aging is routinely observed in studies of the elderly. Individual differences in neurocognitive aging are also a characteristic of other species, such as rodents and non-human primates. In particular, investigations at behavioral, brain systems, cellular and molecular levels of analysis have provided much information on the basis for individual differences in neurocognitive aging among healthy outbred rats. These findings are likely to be relevant to an understanding of the effects of aging on the brain, apart from neurodegenerative conditions, such as Alzheimer’s disease, which do not naturally occur in rodents. Here we review and integrate those findings in a model supporting the concept that certain features of cognitive decline are caused by distributed alterations in the medial temporal lobe, which alter the information processing functions of the hippocampal formation. An additional emerging concept from this research is that preserved abilities at older ages may depend on adaptive changes in the hippocampal system that distinguish successful aging.
- 25 November 2006
- Published by Springer Nature in AGE
- Vol. 28 (3) , 221-233
Individual differences in neurocognitive aging of the medial temporal lobe
A wide spectrum of outcomes in the cognitive effects of aging is routinely observed in studies of the elderly. Individual differences in neurocognitive aging are also a characteristic of other species, such as rodents and non-human primates. In particular, investigations at behavioral, brain systems, cellular and molecular levels of analysis have provided much information on the basis for individual differences in neurocognitive aging among healthy outbred rats. These findings are likely to be relevant to an understanding of the effects of aging on the brain, apart from neurodegenerative conditions, such as Alzheimer’s disease, which do not naturally occur in rodents. Here we review and integrate those findings in a model supporting the concept that certain features of cognitive decline are caused by distributed alterations in the medial temporal lobe, which alter the information processing functions of the hippocampal formation. An additional emerging concept from this research is that preserved abilities at older ages may depend on adaptive changes in the hippocampal system that distinguish successful aging.