Tiffany F. Hughes
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Tiffany F. Hughes has a total of 73 co-authors. Here are the top co-authors by number of shared publications:
Mary Ganguli
Department of Psychiatry, University of Pittsburgh, Pittsburgh PA, USA; Department of Neurology, University of Pittsburgh, Pittsburgh PA, USA; Department of Epidemiology, University of Pittsburgh, Pittsburgh PA, USA
6 shared publicationsChung-Chou H. Chang
Department of Medicine; University of Pittsburgh School of Medicine; Pittsburgh PA USA
4 shared publications- Jason D. Flatt
Department of Social and Behavioral Health, School of Public Health, University of Nevada, Las Vegas, NV 89154, USA
3 shared publications Bo Fu
Department of Biostatistics, Graduate School of Public Health; University of Pittsburgh; Pittsburgh PA USA
2 shared publicationsJoni Vander Bilt
Epidemiology (JVB, MG), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
2 shared publicationsA. R. Borenstein
From the Department of Psychiatry (T.F.H.), University of Pittsburgh, PA; the Department of Epidemiology and Biostatistics (A.R.B., E.S., Y.W.), University of South Florida, Tampa; and the Group Health Center for Health Studies (E.B.L.), University of Washington, Seattle
1 shared publication
Latest Publications
- 3 April 2015
- Published by Taylor & Francis in Activities, Adaptation & Aging
- Vol. 39 (2) , 109-132
A Qualitative Study on the Types and Purposes of Social Activities in Late Life
This qualitative study examines older adults’ subjective views on the types and purposes of social activities. In-depth interviews were conducted with a purposive sample of 20 older adults, with low (n = 10) and high (n = 10) memory performance. We used grounded theory methods to analyze the narrative data. Four types of social activities—altruism, creativity, game, and motion—were identified. The purpose of social activities included enjoyment, relaxation, stimulation, and belongingness. Those in the low memory group seemed to face more barriers to participation. Different types of social activities may be important for cognitive health and well-being.
- 3 April 2015
- Published by Taylor & Francis in Activities, Adaptation & Aging
- Vol. 39 (2) , 109-132
A Qualitative Study on the Types and Purposes of Social Activities in Late Life
This qualitative study examines older adults’ subjective views on the types and purposes of social activities. In-depth interviews were conducted with a purposive sample of 20 older adults, with low (n = 10) and high (n = 10) memory performance. We used grounded theory methods to analyze the narrative data. Four types of social activities—altruism, creativity, game, and motion—were identified. The purpose of social activities included enjoyment, relaxation, stimulation, and belongingness. Those in the low memory group seemed to face more barriers to participation. Different types of social activities may be important for cognitive health and well-being.
- 12 February 2015
- Published by Wiley in Alzheimer's & Dementia
- Vol. 11 (11) , 1377-1384
Independent and combined effects of cognitive and physical activity on incident MCI
Introduction: The objective of this study was to examine the independent and combined influences of late‐life cognitive activity (CA) and physical activity (PA) on the risk of incident mild cognitive impairment (MCI).Methods: We used interval censored survival modeling to examine the risk of incident MCI (Clinical Dementia Rating [CDR] = 0.5) as a function of CA (high vs. low) and at least moderate intensity PA (any vs. none) among 864 cognitively normal (CDR = 0) older adults.Results: During three annual follow‐up waves, 72 participants developed MCI. Compared with low CA with no PA, significant reductions in risk for MCI were observed for high CA with any PA (hazards ratio (HR) = 0.20, 95% confidence interval (CI) 0.07–0.52) and low CA with any PA (HR = 0.52, 95% CI 0.29–0.93), but not for high CA without PA (HR = 0.94, 95% CI 0.45–1.95).Discussion: These findings suggest that a combination of CA and PA may be most efficacious at reducing the risk for cognitive impairment.
- 12 February 2015
- Published by Wiley in Alzheimer's & Dementia
- Vol. 11 (11) , 1377-1384
Independent and combined effects of cognitive and physical activity on incident MCI
Introduction: The objective of this study was to examine the independent and combined influences of late‐life cognitive activity (CA) and physical activity (PA) on the risk of incident mild cognitive impairment (MCI).Methods: We used interval censored survival modeling to examine the risk of incident MCI (Clinical Dementia Rating [CDR] = 0.5) as a function of CA (high vs. low) and at least moderate intensity PA (any vs. none) among 864 cognitively normal (CDR = 0) older adults.Results: During three annual follow‐up waves, 72 participants developed MCI. Compared with low CA with no PA, significant reductions in risk for MCI were observed for high CA with any PA (hazards ratio (HR) = 0.20, 95% confidence interval (CI) 0.07–0.52) and low CA with any PA (HR = 0.52, 95% CI 0.29–0.93), but not for high CA without PA (HR = 0.94, 95% CI 0.45–1.95).Discussion: These findings suggest that a combination of CA and PA may be most efficacious at reducing the risk for cognitive impairment.
- 22 January 2014
- Published by Wiley in International Journal of Geriatric Psychiatry
- Vol. 29 (9) , 890-898
Interactive video gaming compared with health education in older adults with mild cognitive impairment: a feasibility study
Objective We evaluated the feasibility of a trial of Wii interactive video gaming, and its potential efficacy at improving cognitive functioning compared with health education, in a community sample of older adults with neuropsychologically defined mild cognitive impairment. Methods Twenty older adults were equally randomized to either group‐based interactive video gaming or health education for 90 min each week for 24 weeks. Although the primary outcomes were related to study feasibility, we also explored the effect of the intervention on neuropsychological performance and other secondary outcomes. Results All 20 participants completed the intervention, and 18 attended at least 80% of the sessions. The majority (80%) of participants were “very much” satisfied with the intervention. Bowling was enjoyed by the most participants and was also rated the highest among the games for mental, social, and physical stimulation. We observed medium effect sizes for cognitive and physical functioning in favor of the interactive video gaming condition, but these effects were not statistically significant in this small sample. Conclusion Interactive video gaming is feasible for older adults with mild cognitive impairment, and medium effect sizes in favor of the Wii group warrant a larger efficacy trial. Copyright © 2014 John Wiley & Sons, Ltd.
- 22 January 2014
- Published by Wiley in International Journal of Geriatric Psychiatry
- Vol. 29 (9) , 890-898
Interactive video gaming compared with health education in older adults with mild cognitive impairment: a feasibility study
Objective We evaluated the feasibility of a trial of Wii interactive video gaming, and its potential efficacy at improving cognitive functioning compared with health education, in a community sample of older adults with neuropsychologically defined mild cognitive impairment. Methods Twenty older adults were equally randomized to either group‐based interactive video gaming or health education for 90 min each week for 24 weeks. Although the primary outcomes were related to study feasibility, we also explored the effect of the intervention on neuropsychological performance and other secondary outcomes. Results All 20 participants completed the intervention, and 18 attended at least 80% of the sessions. The majority (80%) of participants were “very much” satisfied with the intervention. Bowling was enjoyed by the most participants and was also rated the highest among the games for mental, social, and physical stimulation. We observed medium effect sizes for cognitive and physical functioning in favor of the interactive video gaming condition, but these effects were not statistically significant in this small sample. Conclusion Interactive video gaming is feasible for older adults with mild cognitive impairment, and medium effect sizes in favor of the Wii group warrant a larger efficacy trial. Copyright © 2014 John Wiley & Sons, Ltd.
- Open Access
- 6 November 2013
- Published by Springer Nature in BMC Neurology
- Vol. 13 (1) , 165
COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups
A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders. Longitudinal studies of cognitive ageing and dementia with at least 500 individuals aged 60 years or over are eligible and invited to be members of COSMIC. There are currently 17 member studies, from regions that include Asia, Australia, Europe, and North America. A Research Steering Committee has been established, two meetings of study leaders held, and a website developed. The initial attempts at harmonising key variables like neuropsychological test scores are in progress. The challenges of international consortia like COSMIC include efficient communication among members, extended use of resources, and data harmonisation. Successful harmonisation will facilitate projects investigating rates of cognitive decline, risk and protective factors for mild cognitive impairment, and biomarkers of mild cognitive impairment and dementia. Extended implications of COSMIC could include standardised ways of collecting and reporting data, and a rich cognitive ageing database being made available to other researchers. COSMIC could potentially transform our understanding of the epidemiology of cognitive ageing, and have a world-wide impact on promoting successful ageing.
- 6 November 2013
- Published by Springer Nature in BMC Neurology
- Vol. 13 (1) , 165
Open AccessCOSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups
A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders. Longitudinal studies of cognitive ageing and dementia with at least 500 individuals aged 60 years or over are eligible and invited to be members of COSMIC. There are currently 17 member studies, from regions that include Asia, Australia, Europe, and North America. A Research Steering Committee has been established, two meetings of study leaders held, and a website developed. The initial attempts at harmonising key variables like neuropsychological test scores are in progress. The challenges of international consortia like COSMIC include efficient communication among members, extended use of resources, and data harmonisation. Successful harmonisation will facilitate projects investigating rates of cognitive decline, risk and protective factors for mild cognitive impairment, and biomarkers of mild cognitive impairment and dementia. Extended implications of COSMIC could include standardised ways of collecting and reporting data, and a rich cognitive ageing database being made available to other researchers. COSMIC could potentially transform our understanding of the epidemiology of cognitive ageing, and have a world-wide impact on promoting successful ageing.
- Open Access
- 21 December 2012
- Published by Elsevier in International Psychogeriatrics
- Vol. 25 (4) , 587-595
Engagement in social activities and progression from mild to severe cognitive impairment: the MYHAT study
- 21 December 2012
- Published by Elsevier in International Psychogeriatrics
- Vol. 25 (4) , 587-595
Open AccessEngagement in social activities and progression from mild to severe cognitive impairment: the MYHAT study
- 1 October 2012
- Published by Elsevier in The American Journal of Geriatric Psychiatry
- Vol. 20 (10) , 836-844
Mild Cognitive Deficits and Everyday Functioning Among Older Adults in the Community: The Monongahela-Youghiogheny Healthy Aging Team Study
- 1 October 2012
- Published by Elsevier in The American Journal of Geriatric Psychiatry
- Vol. 20 (10) , 836-844
Mild Cognitive Deficits and Everyday Functioning Among Older Adults in the Community: The Monongahela-Youghiogheny Healthy Aging Team Study
- 26 July 2010
- Published by SAGE Publications in American Journal of Alzheimer's Disease and Other Dementias®
- Vol. 25 (5) , 432-438
Engagement in Reading and Hobbies and Risk of Incident Dementia: The MoVIES Project
Objective: To examine whether there is an association between engagement in reading and hobbies and dementia risk in late life. Methods: A total of 942 members of a population-based, prospective cohort study were followed biennially to identify incident dementia cases. Cox proportional hazards models were used to estimate the risk of dementia in relation to baseline total number of activities and time commitment to reading and hobbies. Results: A lower risk for dementia was found for a greater number of activities and for a high (about 1 hour each day) compared with low (less than 30 minutes each day) weekly time commitment to hobbies, independent of covariates. Only the protective effect of hobbies remained after methods were used to minimize bias due to potential preclinical dementia. Conclusion: Engaging in hobbies for 1 or more hours every day might be protective against dementia in late life.
- 26 July 2010
- Published by SAGE Publications in American Journal of Alzheimer's Disease and Other Dementias®
- Vol. 25 (5) , 432-438
Engagement in Reading and Hobbies and Risk of Incident Dementia: The MoVIES Project
Objective: To examine whether there is an association between engagement in reading and hobbies and dementia risk in late life. Methods: A total of 942 members of a population-based, prospective cohort study were followed biennially to identify incident dementia cases. Cox proportional hazards models were used to estimate the risk of dementia in relation to baseline total number of activities and time commitment to reading and hobbies. Results: A lower risk for dementia was found for a greater number of activities and for a high (about 1 hour each day) compared with low (less than 30 minutes each day) weekly time commitment to hobbies, independent of covariates. Only the protective effect of hobbies remained after methods were used to minimize bias due to potential preclinical dementia. Conclusion: Engaging in hobbies for 1 or more hours every day might be protective against dementia in late life.
- 1 May 2010
- Published by Elsevier in The American Journal of Geriatric Psychiatry
- Vol. 18 (5) , 413-420
Midlife Fruit and Vegetable Consumption and Risk of Dementia in Later Life in Swedish Twins
- 1 May 2010
- Published by Elsevier in The American Journal of Geriatric Psychiatry
- Vol. 18 (5) , 413-420
Midlife Fruit and Vegetable Consumption and Risk of Dementia in Later Life in Swedish Twins
- 1 February 2010
- Published by Taylor & Francis in Aging Health
- Vol. 6 (1) , 111-121
Promotion of Cognitive Health Through Cognitive Activity in the Aging Population
There is both popular and scientific interest in keeping the brain young and avoiding cognitive impairment and dementia. Older adults may be able to modify their cognitive health status through certain health behaviors. The aim of this review is to highlight the potential impact that cognitive activity may have on cognitive health outcomes in late life. Evidence from observational studies and randomized, controlled trials suggests that engagement in activities that are cognitively stimulating is beneficial to cognitive functioning. There are many issues and questions that need to be addressed before specific recommendations can be made at the population level or to individual patients. However, older adults should be encouraged to stay active and to try new and challenging activities in general to promote their cognitive and overall health.
- 1 February 2010
- Published by Taylor & Francis in Aging Health
- Vol. 6 (1) , 111-121
Promotion of Cognitive Health Through Cognitive Activity in the Aging Population
There is both popular and scientific interest in keeping the brain young and avoiding cognitive impairment and dementia. Older adults may be able to modify their cognitive health status through certain health behaviors. The aim of this review is to highlight the potential impact that cognitive activity may have on cognitive health outcomes in late life. Evidence from observational studies and randomized, controlled trials suggests that engagement in activities that are cognitively stimulating is beneficial to cognitive functioning. There are many issues and questions that need to be addressed before specific recommendations can be made at the population level or to individual patients. However, older adults should be encouraged to stay active and to try new and challenging activities in general to promote their cognitive and overall health.