Máximo Bernabeu-Wittel

Máximo Bernabeu-Wittel

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Current Organizations / Institutes

The organizations/institutes from the scholar's latest article

Previous Organizations / Institutes

The organizations / institutes from the scholar's other articles in the past ten years


Máximo Bernabeu-Wittel has a total of 841 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Identification and management of sarcopenia in patients with multimorbidity: An EFIM critically appraised and adapted guideline

    by M. Bernabeu-Wittel, I. Marín-León, C. Angermann, P. Cubo-Romano, Z. Cvetković, A. Dima, M. Fissah, J.A. García-García, S. García-Rubio, E. Kravvariti, et al.

  • Open Access

    Impact of Point-of-Care Ultrasound on the Management of Abdominal Pain in the Emergency Department: A Quasi-Experimental Study

    by Laura Carbajo Martín, Ignacio Párraga-Martínez, Luis Matías Beltrán-Romero, Máximo Bernabeu Wittel, Northern Huelva Health Management Area Research Group

    Objectives: To evaluate the impact of Point-of-Care Ultrasound (POCUS) performed by family physicians on the management of abdominal pain in the emergency department, assessing its effect on length of stay, performance of complementary diagnostic tests, diagnostic concordance, and patient satisfaction. Methods: Quasi-experimental pilot study with a control group conducted in a hospital emergency department. A total of 222 adult patients with abdominal pain were included and allocated according to the attending professional (with or without ultrasound training). Clinical, care-related, and patient-satisfaction variables (SERVPERF questionnaire) were analyzed. Non-parametric statistical tests were used, and multiple linear regression analyses were performed. Results: The POCUS group showed a shorter length of stay (3.46 vs. 4.41 h; p = 0.022) and a lower number of plain radiographies (16.8% vs. 69.9%; p < 0.001) and CT scans (p = 0.034). Diagnostic concordance was significantly higher in the experimental group (99.2% vs. 75.7%; p < 0.001). Overall satisfaction with received care was also higher in the intervention group (p < 0.001), with significant differences observed across all evaluated dimensions. The multivariate model explained 26.6% of the variability, with patient satisfaction emerging as a positive predictor. Conclusions: POCUS improves the quality of care in emergency departments by reducing length of stay and the use of complementary diagnostic tests while increasing diagnostic accuracy and patient satisfaction. Its implementation can be considered an effective and potentially cost-effective strategy; however, further studies with greater methodological robustness are required to validate the development of standardized composite indexes.

  • Open Access

    Impact of Point-of-Care Ultrasound on the Management of Abdominal Pain in the Emergency Department: A Quasi-Experimental Study

    by Laura Carbajo Martín, Ignacio Párraga-Martínez, Luis M Beltrán Romero, Máximo Bernabeu Wittel, Northern Huelva Health Management Area Research Group

    Objectives: To evaluate the impact of Point-of-Care Ultrasound (POCUS) performed by family physicians on the management of abdominal pain in the emergency department, assessing its effect on length of stay, performance of complementary diagnostic tests, diagnostic concordance, and patient satisfaction. Methods: Quasi-experimental pilot study with a control group conducted in a hospital emergency department. A total of 222 adult patients with abdominal pain were included and allocated according to the attending professional (with or without ultrasound training). Clinical, care-related, and patient-satisfaction variables (SERVPERF questionnaire) were analyzed. Non-parametric statistical tests were used, and multiple linear regression analyses were performed. Results: The POCUS group showed a shorter length of stay (3.46 vs. 4.41 hours; p=0.022) and a lower number of plain radiographies (16.8% vs. 69.9%; pp=0.034). Diagnostic concordance was significantly higher in the experimental group (99.2% vs. 75.7%; pp Conclusions: POCUS improves the quality of care in emergency departments by reducing length of stay and the use of complementary diagnostic tests while increasing diagnostic accuracy and patient satisfaction. Its implementation can be considered an effective and potentially cost-effective strategy; however, further studies with greater methodological robustness are required to validate the development of standardized composite indexes.

  • Open Access

    Ultrasound-Guided Lateral Femoral Cutaneous Nerve Block in Patients with Meralgia Paresthetica: Technical Description and Case Series of 11 Patients

    by Bosco Baron-Franco, Luis Beltran-Romero, Carlos Jiménez-Juan, Dolores Nieto-Martin, Santiago Rodriguez-Suarez, Maximo Bernabeu-Wittel

    Background: Meralgia paresthetica is a neuropathic pain syndrome caused by compression of the lateral femoral cutaneous nerve (LFCN). While often self-limited, a subset of patients develops persistent symptoms requiring interventional management. Ultrasound guidance has improved accuracy and safety in peripheral nerve blocks, but evidence from Internal Medicine-led procedures remains limited. Methods: We performed a retrospective, observational case series including all patients aged ≥17 years who underwent ultrasound-guided LFCN blocks at Virgen del Rocío University Hospital between 2016 and 2024. Demographic data, comorbidities, procedural details, complications, and clinical outcomes were collected. Symptomatic response and recurrence were assessed descriptively. Results: Eleven patients were included (10 women; median age 56 years). The most frequent comorbidities were obesity (45.5%) and type 2 diabetes mellitus (18.2%). Clinical improvement following LFCN block was achieved in 10 of 11 patients (91%). Three patients (27%) experienced recurrence, with a median time to recurrence of 24 months; two underwent a second successful block, and one showed spontaneous resolution. No major complications occurred, and only one patient developed a mild, self-limited local reaction. Conclusions: Ultrasound-guided LFCN block is a safe, well-tolerated, and highly effective intervention for patients with persistent meralgia paresthetica. Outcomes achieved by an Internal Medicine specialist appear consistent with previously published reports from anesthesiology settings, underscoring the value of point-of-care ultrasound as a practical and precise tool for managing neuropathic pain within Internal Medicine settings.


  • Open Access

    Bedside Clinical Ultrasound Performed by Family Physicians in Adult Patients With Abdominal Pain in a Hospital Emergency Department: Protocol for a Pilot Quasi-Experimental Study

    by Laura Carbajo Martín, Ignacio Párraga-Martínez, Luis M Beltrán-Romero, Máximo Bernabeu Wittel, Northern Huelva Health Management Area Research Group

    Background: Point-of-care ultrasound is a valuable bedside tool that, with adequate training, can reduce diagnostic uncertainty and improve clinical accuracy. Abdominal pain is a frequent complaint in emergency departments and often requires imaging for appropriate management. Objective: This study aims to assess the impact of bedside clinical ultrasound performed by family physicians on length of stay, number of basic radiological tests, and need for further diagnostic evaluations in adult patients with abdominal pain. Methods: This is a pilot quasi-experimental study assessing feasibility and viability, with a nonrandomized control group, to be conducted in the Emergency Department of Hospital Comarcal de Riotinto. Adult patients (≥18 y) presenting with abdominal pain will be included. Both groups will receive standard care. In the intervention group, bedside ultrasound will be performed by trained family physicians; in the control group, ultrasound will be performed by radiologists only if deemed necessary. The primary outcome is the improvement in quality of care, assessed through a reduction in emergency department length of stay, fewer basic radiology tests requested, and diagnostic concordance. Secondary outcomes include the need for additional diagnostic studies and the appropriateness of referrals, evaluated through 1-month follow-up and reconsultation. Results: The first phase of the project began in 2023 with the validation of the data collection form. Subsequently, the patient satisfaction questionnaire was validated, and the results were published in the journal Care Primary . The study has received external funding, and patient recruitment is currently ongoing and expected to be completed in December 2025. Conclusions: This study aims to demonstrate the clinical and organizational benefits of implementing bedside ultrasound by family physicians in emergency care.

  • Percutaneous core needle biopsy guided by ultrasound: a narrative review

    by Yale Tung-Chen, Francisco Javier Teigell Muñoz, Sergio Aleman Belando, Bosco Barón Franco, Luis Beltrán Romero, Máximo Bernabeu-Wittel, Guillermo Cuevas Tascón, Juan Delgado-Cuesta, Cristina Escorial Moya, Juan Sebastián Espinosa Serna, et al.

    Ultrasound-guided core needle biopsy (CNB) is a highly effective technique for diagnosing tumoral and inflammatory/infectious diseases. The procedure provides real-time visualization of anatomical structures such as vessels and nerves, reducing complications and enhancing accuracy. Traditionally performed by interventional radiologists, CNB can also be safely and effectively conducted by another specialists, including general physicians, thanks to the widespread availability of Point-of-Care Ultrasound. This not only improves and expedites the diagnostic process but also facilitates access to minimally invasive interventions by clinical services, establishing ultrasound-guided CNB as an essential tool for general physicians.


  • Open Access

    The Influence of Adherence to a Mediterranean Diet on Decompensation in Patients with Chronic Heart Failure

    by Jose Jiménez-Torres, Carlos Jiménez-Juan, Ana Villa-Martínez, Marta Gutiérrez-García, Lourdes Moreno-Gaviño, Reyes Aparicio-Santos, Ángela Romero-Muñoz, M. José Goncet-Cansino, Bosco Barón-Franco, Máximo Bernabeu-Wittel

    Background: Chronic heart failure (CHF) is a major health problem, representing the main cause of hospitalization in people over 65 years of age. Several studies have associated the Mediterranean diet with a cardioprotective function, improving prognoses in patients with high cardiovascular risk. Our main objective is to determine whether higher adherence to the Mediterranean diet is associated with a lower severity of CHF, based on the number of decompensations and disease complications. Methods: This study was a single-center retrospective cohort study conducted at the Virgen del Rocío Hospital (Seville). Adherence to a Mediterranean diet was determined by the Mediterranean Diet Adherence Screener (MEDAS) in patients with chronic heart failure in a state of clinical stability, the number of decompensations in the 12 months before inclusion, cardiac biomarkers (NT-proBNP and CA125), evaluation of dyspnea, and quality of life assessment according to NYHA and KCCQ scales and analytical profiles. Results: Seventy-two patients were included (35 with high adherence to the Mediterranean diet and 37 with low adherence). The mean age was 81.29 ± 0.86 years. A trend towards fewer decompensations (1.49 ± 0.14 vs. 1.92 ± 0.17, p = 0.054) and lower NT-proBNP values (2897.02 ± 617.16 vs. 5227.96 ± 1047.12; p = 0.088) was observed in patients with high adherence compared to those with low adherence to the Mediterranean diet. Conclusions: Our results suggest that patients with CHF and high adherence to the Mediterranean diet have a tendency towards an improved cardiac profile, indicated by fewer decompensations and lower NT-proBNP levels. Future clinical trials are needed to substantiate these hypotheses.


  • Open Access

    Low Muscle Strength Assessed with Dynamometry in Elderly Polypathological Patients with Acute Heart Failure: PROFUND-IC Registry

    by Alicia Guzmán-Carreras, Jorge San Miguel-Agudo, Mateo Paz-Cabezas, Máximo Bernabeu-Wittel, Nuria Muñoz-Rivas, Beatriz Sánchez-Sauce, Fernando Aguilar-Rodríguez, Luis Cabeza-Osorio, Emmanuel Andrès, Noel Lorenzo-Villalba, et al.

    Background: Sarcopenia is a comorbidity associated with heart failure, which aggravates its prognosis. Objectives: To analyze the differential characteristics of polypathological patients with acute heart failure (AHF) based on the presence of low muscle strength, as well as to study whether this condition is associated with a worse prognosis. Methods: An observational study of 377 patients with a diagnosis of acute heart failure from the prospective multicentric PROFUND-IC registry was carried out. The main variable is low muscle strength, which is assessed with dynamometry or prehensile strength. Epidemiological and anthropometric characteristics, as well as associated comorbidities, were analyzed. Likewise, the etiology of the AHF episode, the number of admissions in the previous year, and the NYHA scale were also included. Finally, scores on functionality, treatment established, and mortality and readmission rates were studied. Quantitative variables are described as mean, and standard deviation, and qualitative variables are expressed as absolute numbers and percentages. A descriptive and bivariate analysis was performed according to the presence of low muscle strength (handgrip p < 0.001), with more cognitive impairment (11.9% vs. 0%, p = 0.021), worse functional class (p = 0.016), lower scores in the Barthel index and Rockwood scale (p < 0.001), and higher in the PROFUND index (p < 0.001). They had higher rates of readmission and mortality without statistically significant differences. The PROFUND index is significantly associated with low muscle strength (OR 1.19, CI (1.09–1.31), p < 0.001). Conclusions: Elderly polypathological patients with acute heart failure and low muscle strength have a higher PROFUND index and a lower probability of survival per year.


  • Open Access

    Influence of Adherence to a Mediterranean Diet on Descompensation in Patients with Chronic Heart Failure

    by Jose Jiménez-Torres, Carlos Jiménez-Juan, Ana Villa-Martínez, Marta Gutiérrez-García, Lourdes Moreno-Gaviño, Reyes Aparicio-Santos, Ángela Romero-Muñoz, M José Goncet-Cansino, Bosco Barón-Franco, Máximo Bernabeu-Wittel

    Background: Chronic Heart failure (CHF)constitutes a major health problem, representing the leading cause of hospitalization in people over 65 years old. Several studies have associated the Mediterranean diet with a cardioprotective function, improving prognosis in patients with high cardiovascular risk. Our main objective is to determine whether greater adherence to the Mediterranean diet is associated with a lower severity of CHF, depending on the number of heart failure decompensations and complications of the disease. Methods: The study was a single-center restrospective cohort study conducted at the Virgen del Rocío Hospital (Seville). Adherence to a Mediterranean diet was determined by the Mediterranean Diet Adherence Screener (MEDAS) in patients with chronic heart failure in a state of clinical stability, and their cardiac and analytical profiles were evaluated. Results: Seventy-two patients were included (35 with high adherence to the Mediterranean diet and 37 with low adherence). The average age was 81.29 ± 0.86 years. A trend towards fewer cardiac decompensations (1,49 ± 0,14 vs 1,92 ± 0,17), p= 0,054) and lower NT-proBNP values 2897,02 ± 617,16 vs 5227,96 ± 1047,12; p = 0,088) was observed in patients with high adherence compared to those with low adherence to the Mediterranean diet. Conclusions: Our results suggest that patients with CHF and high adherence to the Mediterranean diet have a tendency towards improved cardiac profile, indicated by fewer decompensations and lower NT-proBNP levels. Future clinical trials are needed to substantiate these hypotheses.


  • Open Access

    Impact of hyponatremia in patients hospitalized in Internal Medicine units: Hyponatremia in Internal Medicine units

    by Jara Eloísa Ternero-Vega, Carlos Jiménez-De-Juan, Javier Castilla-Yelamo, Vanesa Cantón-Habas, Elena Sánchez-Ruiz-Granados, Miguel Ángel Barón-Ramos, Guillermo Ropero-Luis, Juan Gómez-Salgado, Máximo Bernabeu-Wittel

    The aim of this study was to analyze the impact and the clinical and evolutionary characteristics of hypotonic hyponatremia in patients hospitalized in Internal Medicine units. Prospective multicenter observational study of patients with hypotonic hyponatremia (P = .037). Mortality at 1 year and readmissions were high (31% and 53% of patients, respectively). Hyponatremia was common in Internal Medicine areas, with hypervolemic hyponatremia being the most frequent type. The mortality rate was high during admission and at follow-up; yet there is a margin for improvement in the clinical management of this condition.