Jeanne F. Nichols

Although prevalence of obesity and incidence of total joint arthroplasty (TJA) have dramatically increased over the last two decades in the U.S., little is known of the preoperative and postoperative weight patterns of patients undergoing TJA. To describe the preoperative and postoperative weight patterns of patients undergoing TJA and evaluate characteristics associated with these patterns. Retrospective cohort study. A cohort of patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) between January 1, 2008, and December 31, 2010, was identified. Using weight obtained at patient encounters, patients were categorized into gainers (increased weight by 5%), losers (decreased weight by 5%), or remained the same (changed < 5%) for the preoperative and postoperative periods. Patients were characterized by sex, age, and race. Weight change before and after TJA. Of 30,632 patients with TJA identified, 34.5% underwent THA and 65.5% had TKA. Most patients remained the same weight during the year before (THA, 71.5%; TKA, 75.7%) and after the procedure (64.0% and 68.5%, respectively). Before and after THA, men were less likely to lose or gain weight than were women. Older patients were less likely to gain weight. Among patients undergoing TKA, men were less likely to lose weight preoperatively or postoperatively, or gain weight postoperatively, and older patients were less likely to gain weight before or after arthroplasty. Some racial associations with weight patterns were observed. Specific groups are more susceptible to weight change and could benefit from weight management interventions.

This study tracked changes in bone mineral density (BMD) over a 7-year period in competitive male master cyclists (n = 19) and nonathletes (n = 18). Participants completed health/exercise history and food frequency (for calcium intake) questionnaires and underwent BMD testing by dual-energy X-ray absorptiometry. At initial and 7-year assessments, there was a consistent pattern of lower BMD in cyclists compared to nonathletes at all bone sites measured. Repeated measures analysis of covariance adjusted for changes in body mass index, lean mass, calcium intake, and exercise habits indicated a significant interaction at the total body site, indicating greater BMD decline in cyclists than nonathletes (p < 0.05). Among all study participants, those who reported participating in weight training or impact exercise since the baseline assessment lost significantly less BMD at the spine and femoral neck compared to participants who reported no weight training/impact exercise since baseline (p < 0.05). A significantly greater percentage of cyclists than nonathletes met the International Society of Clinical Densitometry criteria for osteopenia or osteoporosis at baseline (84.2% vs. 50.0%) and at follow-up (89.5% vs. 61.1%, p < 0.05). Further, 6 of the 19 (31.6%) cyclists who had osteopenia at baseline became osteoporotic, compared to 1 (5.6%) of the nonathletes. The high percentage of male master cyclists with low BMD, combined with a high risk for fracture from falls associated with competitive cycling, warrant attention among this population. Coaches and health professionals interacting with cyclists need to promote alternative exercise such as weight training, plyometrics, or other high impact activity as a complement to cycle training to help minimize bone loss in this population.

Purpose.: To test effects of parent/child training designed to increase calcium intake, bone-loading physical activity (PA), and bone density. Design.: Two-group randomized controlled trial. Setting.: Family-based intervention delivered at research center. Subjects.: 117 healthy children aged 10–13 years (58.1% female, 42.7% Hispanic, 40.2% White). Ninety-seven percent of participants had at least one parent graduate from high school and 37.2 % had at least one parent graduate from a 4-year university. Intervention.: Children and parents were randomly assigned to diet and exercise (experimental) or injury prevention (control) interventions. Children were taught in eight weekly classes how to engage in bone-loading PA and eat calcium-rich foods or avoid injuries. Parents were taught behavior management techniques to modify children's behaviors. Measures.: Measures at baseline and at 3, 9, and 12 months included 24-hour diet and PA recalls, and bone mineral density (BMD) by dual-energy x-ray absorptiometry. Analysis.: Analysis of variance and generalized estimating equations (GEE) assessed group by time differences. Comparisons were conducted separately for boys and girls. Results.: For boys, cross-sectional differences between experimental and control groups were achieved for 3- and 9-month calcium intake (1352 vs. 1052 mg/day, 1298 vs. 970 mg/day, p < .05). For girls, marginal cross-sectional differences were achieved for high-impact PA at 12 months (p < .10). For calcium intake, a significant group by time interaction was observed from pretest to posttest for the full sample (p = .008) and for girls (p = .006) but not for boys. No significant group by time differences in calcium were observed across the follow-up period. No group by time differences were observed for high-impact PA. Among boys, longitudinal group by time differences reached significance for total hip BMD (p = .045) and femoral neck BMD (p = .033), even after adjusting for skeletal growth. Similar differential increases were observed among boys for bone mineral content (BMC) at the hip (p = .068) and total body (p = .054) regions. No significant group by time interaction effects were observed for girls at any bone site for BMD. For BMC, control girls showed a significant increase (p = .03) in spine BMC compared to intervention girls. Conclusion.: This study demonstrated that parent/preteen training can increase calcium intake and attenuate the decline in high-impact PA. Results suggest that more powerful interventions are needed to increase activity levels and maximize bone mineral accrual during preadolescent years.

Overweight or obesity is an established negative prognostic factor in breast cancer. Co-morbidities associated with obesity, including cardiovascular disease (CVD), may negatively impact quality of life and survival in this population. Our purpose was to determine the effect of a cognitive behavioral therapy (CBT) intervention for weight loss through exercise and diet modification on risk factors for recurrence of breast cancer, and risks for CVD associated with obesity. Eighty-five overweight or obese breast cancer survivors were randomly assigned to a once weekly, 16-week intervention or wait-list control group. The intervention incorporated elements of CBT for obesity, addressing a reduction in energy intake, as well exercise, with a goal of an average of 1 h a day of moderate to vigorous activity. Body weight, total and regional body fat (by dual energy X-ray absorptiometry), waist and hip circumference, and blood lipids were assessed at baseline and following 16 weeks of intervention. Results: Seventy six women (89.4%) completed the intervention. Independent t-test to evaluate group differences at 16 weeks showed significant differences in weight, body mass index, percent fat, trunk fat, leg fat, as well as waist and hip circumference between intervention and control groups (P ≤ 0.05). Furthermore, levels of triglycerides and total cholesterol/high density lipoprotein cholesterol levels were also significantly reduced following the intervention. These results indicate that 16 weeks of a CBT program for weight management may reduce obesity and CVD risk in overweight breast cancer survivors.

Objective To estimate the prevalence of the female athlete triad (disordered eating, menstrual irregularity, and low bone mass) among high school athletes. Design Observational cross-sectional study. Setting High school. Participants Female athletes (n= 170) representing 8 sports were recruited from 6 high schools in southern California. Main Outcome Measures Disordered eating and menstrual status were determined by interviewer-assisted questionnaires. Bone mineral density was measured by dual-energy x-ray absorptiometry of the hip, spine (L1-L4), and total body. Results Among all athletes, 18.2%, 23.5%, and 21.8% met the criteria for disordered eating, menstrual irregularity, and low bone mass, respectively. Ten girls (5.9%) met criteria for 2 components of the triad, and 2 girls (1.2%) met criteria for all 3 components. Oligomenorrheic/amenorrheic athletes had higher mean ± SD eating restraint (1.55 ± 1.60 vs 1.04 ± 1.27;P = .02) and Eating Disorder Examination Questionnaire global scores (1.68 ± 1.20 vs 1.33 ± 1.14;P = .03) than eumenorrheic athletes. After controlling for age, age at menarche, body mass index, race/ethnicity, and sport type, athletes with oligomenorrhea/amenorrhea had significantly lower mean ± SD bone mineral densities for the trochanter (0.884 ± 0.090 g · cm⁻²) than eumenorrheic athletes (0.933 ± 0.130 g · cm⁻²;P = .04). Conclusions The prevalence of the full female athlete triad was low in our sample; however, a substantial percentage of the athletes may be at risk for long-term health consequences associated with disordered eating, menstrual irregularity, or low bone mass. Preparticipation screening to identify these components should be encouraged as a preventive approach to identify high-risk athletes.