Alain Londero

Call for an Evidence-Based Consensus on Outcome Reporting in Tinnitus Intervention Studies

Second or more surgical procedures on parotid are usually difficult and may induce injury on the facial nerve. The authors report their experience about 42 patients. The choice between a total parotidectomy or a surgical excision of a tumor depends of the number of surgical procedure, the type of initial procedure and the histological type of the tumor. Second surgical procedures for a wrong initial histological diagnosis (11 cases) were always a total parotidectomy with facial nerve preservation. The risk of a partial or total facial palsy is higher after several recurrences (3 of 8 cases). The facial nerve had to be resected in 3 of 9 cases of malignant tumors recurrences. The initial treatment of a tumor of the parotid must be radical so it can prevent for further surgical procedures and then avoid a facial nerve injury.

This paper presents the first case of human genetic hearing loss due to predominant inner hair cell damage investigated by psychoacoustic audiometry, auditory brainstem responses (ABR), evoked acoustic emissions (EAEs), and distortion product otoacoustic emissions (DPOEs). The genetic transmission was an autosomal dominant inheritance. The audiogram pattern was a dominant high-frequency hearing loss. EAE and DPOE properties were normal. Bronx waltzer mutant mouse with genetically determined predominant inner hair cell defects provide an interesting model to study this congenital deafness. This rare congenital deafness with predominant damage to inner hair cells cannot be detected by neonatal screening techniques using EAEs or DPOEs.

Acoustic distorsion products are sounds emitted by the cochlea, in relation with the outer hair cell properties and the micromechanical properties of the Organ of Corti, in response to an acoustic stimulation by two primairies F1 and F2. Acoustic distorsion product 2F1-F2 have been recorded in two populations: 10 normally-hearing subjects and 10 subjects with pure sensorineural hearing losses. Three points are discussed: (i) the test-retest reliability, (ii) the clinical tolerance and (iii) the clinical applications of this test.