B. T. Mathews
Research Subjects
B. T. Mathews has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- John C. Mitchell
Medway Centre for Pharmaceutical Sciences, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, United Kingdom
2 shared publications - Martin John Snowden
School of Science, Medway Campus, University of Greenwich, Central Ave, Gillingham, Chatham Maritime, Kent ME4 4TB, UK
2 shared publications A. E. Beezer
Medway Sciences, Natural Resources Institute, Uniersity of Greenwich, Chatham Maritime, Kent, UK
1 shared publicationA. G. Wright
Pfizer Global Research and Development
1 shared publicationM. J. Hardy
SmithKline Beecham Pharmaceuticals, Coldharbour Road, The Pinnacles, Harlow, Essex, UK
1 shared publicationM. R. Taylor
Pfizer Global Research and Development
1 shared publication
Latest Publications
- 1 December 2004
- Published by Springer Nature in Chromatographia
- Vol. 60 (11-12) , 625-633
Improving Quantitative Measurements for the Evaporative Light Scattering Detector
- 1 December 2004
- Published by Springer Nature in Chromatographia
- Vol. 60 (11-12) , 625-633
Improving Quantitative Measurements for the Evaporative Light Scattering Detector
- 21 May 2001
- Published by Royal Society of Chemistry (RSC) in New Journal of Chemistry
- Vol. 25 (6) , 807-818
The synthesis of immobilised chiral dendrimers
A one pot synthetic approach to amino acid based chiral dendrimers was shown to give good yields for dendrimers with peptide linkages. Using this synthetic strategy, modification of the peripheral functionality is possible, as is the substitution of other amino acids to give mixed amino acid based dendrimers. Immobilization of our dendrimers was accomplished using a coupling method involving the carboxy derivatised dendrimers with an aminopropyl modified silica. The use of 2-ethoxy-1-ethoxy-1,2-dihydroquinoline in a one pot protocol gave enhanced reaction conditions from which silicas bearing very high levels of dendrimer were obtained. Solid state NMR analysis substantiated that the dendrimers were bound to the silica and that they appeared to be structurally intact. These immobilised chiral dendrimers constitute a new class of chiral stationary phases for use in HPLC.
- 21 May 2001
- Published by Royal Society of Chemistry (RSC) in New Journal of Chemistry
- Vol. 25 (6) , 807-818
The synthesis of immobilised chiral dendrimers
A one pot synthetic approach to amino acid based chiral dendrimers was shown to give good yields for dendrimers with peptide linkages. Using this synthetic strategy, modification of the peripheral functionality is possible, as is the substitution of other amino acids to give mixed amino acid based dendrimers. Immobilization of our dendrimers was accomplished using a coupling method involving the carboxy derivatised dendrimers with an aminopropyl modified silica. The use of 2-ethoxy-1-ethoxy-1,2-dihydroquinoline in a one pot protocol gave enhanced reaction conditions from which silicas bearing very high levels of dendrimer were obtained. Solid state NMR analysis substantiated that the dendrimers were bound to the silica and that they appeared to be structurally intact. These immobilised chiral dendrimers constitute a new class of chiral stationary phases for use in HPLC.