AEAlexander L. Eastman

Alexander L. Eastman

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Current Organizations / Institutes

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Previous Organizations / Institutes

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Alexander L. Eastman has a total of 65 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Prospective validation of the Parkland Grading Scale for Cholecystitis

    by Tarik D. Madni, Paul A. Nakonezny, Evan Barrios, Jonathan B. Imran, Audra T. Clark, Luis Taveras, Holly B. Cunningham, Alana Christie, Alexander L. Eastman, Christian T. Minshall, et al.


  • Determining suicide risk in trauma patients using a universal screening program

    by Jonathan B. Imran, Robyn E. Richmond, Tarik D. Madni, Kimberly Roaten, Audra T. Clark, Emily Y. Huang, Ali A. Mokdad, Luis R. Taveras, Kareem R. Abdelfattah, Michael W. Md Cripps, et al.

    BACKGROUND Trauma patients may be at elevated risk for subsequent suicide; however, it is unclear whether patients at risk can be identified during their initial presentation following injury. The objectives of this study were to evaluate the use of a standardized clinical decision support system for suicide risk screening developed by our hospital system and to determine the incidence of positive suicide screenings in our trauma population. METHODS Adult trauma patient screenings were performed by nursing staff during the triage process using the Columbia Suicide Severity Rating Scale, Clinical Practice Screener, Recent (C-SSRS). Adult trauma patients who had a suicide risk screening completed from February 2015 to November 2015 were evaluated retrospectively. Patients were divided into cohorts consisting of those with positive and negative screening assessments. Significance was set at α = 0.05. Statistical analysis was performed using Student t test and a χ2 test where appropriate. RESULTS Overall, 3,623 of 3,712 patients (98%) completed a suicide risk screening during the study period. Those who went unscreened were not evaluated due to altered mental status/intubation/emergent surgery (97%), death (1%), or an unwillingness to cooperate (2%). The suicide risk screening result was positive in 161 of 3,623 patients (4%) in the study cohort. On univariate analysis, patients with a positive suicide risk screen result were more likely to be white (43% vs 32%; p = 0.01), identify English as their primary language (91% vs 73%; p < 0.01), have insurance coverage (48% vs 28%; p < 0.01), and were more likely to initiate a low-level trauma activation (27% vs 16%; p <0.01) than those who had a negative screening result. A positive suicide risk assessment result was moderately associated with patients of white race (odds ratio, 1.83; 95% confidence interval, 1.27–2.65) on multivariable logistic regression. CONCLUSION Our universal suicide screening process identifies an at-risk subpopulation of trauma patients. LEVEL OF EVIDENCE Prognostic study, level III; therapeutic, level IV.


  • CLABSI

    by Tarek Madni, Alexander L. Eastman


  • Active Shooter and Intentional Mass Casualty Events

    by Alexander L. Eastman, Matthew L. Davis

  • Cannabis Use Has Negligible Effects Following Severe Traumatic Injury

    by Kareem R. AbdelFattah, Courtney R. Edwards, Michael W. Cripps, Christian T. Minshall, Herb A. Phelan, Joseph P. Minei, Alexander L. Eastman

    Nearly half of all states have legalized medical marijuana or recreational-use marijuana. As more states move toward legalization, the effects on injured patients must be evaluated. This study sought to determine effects of cannabis positivity at the time of severe injury on hospital outcomes compared with individuals negative for illicit substances and those who were users of other illicit substances. A Level I trauma center performed a retrospective chart review covering subjects over a 2-year period with toxicology performed and an Injury Severity Score (ISS) of more than 16. These individuals were divided into the negative and positive toxicology groups, further divided into the marijuana-only, other drugs-only, and mixed-use groups. Differences in presenting characteristics, hospital length of stay, intensive care unit (ICU) stays, ventilator days, and death were compared. A total of 8,441 subjects presented during the study period; 2,134 (25%) of these had toxicology performed; 843 (40%) had an ISS of more than 16, with 347 having negative tests (NEG); 70 (8.3%) substance users tested positive only for marijuana (MO), 323 (38.3%) for other drugs-only, excluding marijuana (OD), and 103 (12.2%) subjects showed positivity for mixed-use (MU). The ISS was similar for all groups. No differences were identified in Glasgow Coma Scale (GCS), ventilator days, blood administration, or ICU/hospital length of stay when comparing the MO group with the NEG group. Significant differences occurred between the OD group and the NEG/MO/MU groups for GCS, ICU length of stay, and hospital charges. Cannabis users suffering from severe injury demonstrated no detrimental outcomes in this study compared with nondrug users.


  • PTSD in those who care for the injured

    by Kevin Luftman, Jayson Aydelotte, Kevin Rix, Sadia Ali, Katherine Houck, Thomas B. Coopwood, Pedro Teixeira, Alex Eastman, Brian Eastridge, Carlos V.R. Brown, et al.


  • Postoperative Antibiotic Overuse in Uncomplicated Appendicitis: A Single-Center Investigation

    by Madhu Subramanian, Michelle K. Arevalo, Ryan P. Dumas, Erica I. Hodgman, Kareem Abdelfattah, Alexander L. Eastman, Brian H. Williams, Stephen S. Luk, Christian T. Minshall, Michael W. Cripps

  • Prestorage leukoreduction abrogates the detrimental effect of aging on packed red cells transfused after trauma: a prospective cohort study

    by Herb A. Phelan, Alexander L. Eastman, Kim Aldy, Elizabeth A. Carroll, Paul A. Nakonezny, Tiffany Jan, Jessi L. Howard, Yixiao Chen, Randall S. Friese, Joseph P. Minei


  • CTA-Based Screening Reduces Time to Diagnosis and Stroke Rate in Blunt Cervical Vascular Injury

    by Alexander L. Eastman, Vijay Muraliraj, Jason L. Sperry, Joseph P. Minei

    Background: Advances in computed tomography capabilities have enabled trauma surgeons to screen for and diagnose the severity of blunt cervical vascular injury (BCVI) using computed tomographic angiography (CTA) alone. We hypothesized that the use of CTA-alone screening and diagnostic methods would reduce the time interval from admission to diagnosis and, hence, also reduce the stroke rates associated with these injuries. Methods: All patients admitted to a level I trauma center after December 1999 at risk for BCVI were screened. Until March 2005, patients were screened with cervical catheter angiography (CA). Subsequently, a CTA-alone screening/diagnostic program was initiated simultaneously with standardized interdisciplinary treatment guidelines for BCVI. Data for controls were subsequently obtained by reviewing trauma registry records. Results: Of 3012 trauma service admissions from April 2005 to July 2006, 26 patients were found to have BCVI diagnosed by CTA alone. A standardized, injury grade-based set of treatment guidelines were then initiated immediately based on CTA findings. Time to diagnosis and stroke rate in these patients were then compared with 79 patients found to have BCVI from December 1999 to March 2005 during CA-based screening. There were no differences in sex, mean age, Injury Severity Score, head/neck Abbreviated Injury Scale, or arrival Glasgow Coma Scale between the CA and CTA groups. With CA-based screening, the mean ± SD time from trauma center admission to diagnosis was 31.2 ± 41.1 hours. After transition to CTA screening in March 2005, this time was reduced to 2.65 ± 3.3 hours (p < 0.001). During the era of CA-based screening, the overall stroke rate for BCVI at our institution was 15.2% (n = 12 of 79). After the initiation of CTA-based screening, the stroke rate was reduced to 3.8% (n = 1 of 26, p = 0.046). Conclusions: The initiation of a CTA-based screening and diagnostic program, along with interdisciplinary standardized treatment guidelines, reduced the time to diagnosis of BCVI 12-fold and the institutional stroke rate due to BCVI fourfold. This may be due to earlier diagnosis and initiation of definitive therapy.


  • Conductive Electrical Devices: A Prospective, Population-Based Study of the Medical Safety of Law Enforcement Use

    by Alexander L. Eastman, Jeffery C. Metzger, Paul E. Pepe, Fernando L. Benitez, James Decker, Kathy J. Rinnert, Craig A. Field, Randall S. Friese

    To examine police compliance with policies for the proper use of conductive electrical devices (CEDs) and, in turn, track any associated medical events following CED application. Prospective, population-based, 15-month study of police activations of CEDs after their introduction into the police force of a large U.S. city (residential population, 1.25 million). Local policy for use was consistent with the recommendations of International Association of Chiefs of Police. Data collected included age, sex, predefined rationale for use, target distance, activation duration, total energy delivered, policy compliance, and medical findings or events within the first 12 hours. Among 426 consecutive CED activations (November 1, 2004 through January 31, 2006), the suspects' mean age (years +/- standard deviation) was 30 +/- 10 (range, 13-72) years and 90.4% were male. Suspects' mean distance from the officer was 5.0 +/- 4.5 feet (range, 0-21). Reasons for use included: evading or resisting arrest (33.3%, n = 142), public intoxication or disorderly conduct (15.8%, n = 76), interrupting a felony in progress (9.3%, n = 45), and interrupting an assault on an officer or public servant (6.0%, n = 29). Mean total duration of exposures was 8.6 +/- 5.9 seconds, and total energy delivered per suspect was 227 +/- 156 joules. Officers followed policy in all cases and, accordingly, all suspects rapidly received medical evaluation or simple first aid. No suspect required further treatment except one who was later found to have severe toxic hyperthermia and who died within 2 hours of activation despite rapid on-scene intervention. In 5.4% of deployments (n = 23), CED use was deemed to have clearly prevented the use of lethal force by police. Police were compliant with policy in all cases, and, in addition to avoiding the use of lethal force in a significant number of circumstances, the safety of CED use was demonstrated despite one death subsequently attributed to lethal toxic hyperthermia. Collaborative nationwide research using similar registries is strongly recommended to document compliance and ensure ongoing safety monitoring.