Ronghui Lin
Research Subjects
Ronghui Lin has a total of 19 co-authors. Here are the top co-authors by number of shared publications:
Angel R. Fuentes-Pesquera
3 shared publicationsPeter J. Connolly
3 shared publicationsStuart L. Emanuel
3 shared publicationsYanhua Lu
3 shared publicationsLinda K. Jolliffe
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Drug Discovery, 1000 Route 202, Raritan, New Jersey 08869
2 shared publicationsMary Adams
2 shared publications
Latest Publications
- 1 August 2007
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (16) , 4557-4561
Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors
- 1 August 2007
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (16) , 4557-4561
Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors
- 1 June 2005
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 48 (13) , 4208-4211
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities
A series of 1-acyl-1H-[1,2,4]triazole-3,5-diamine analogues were synthesized as cyclin-dependent kinase (CDK) inhibitors. These compounds showed potent and selective CDK1 and CDK2 inhibitory activities and inhibited in vitro cellular proliferation in various human tumor cells. Representative compound 3b demonstrated in vivo efficacy in a human melanoma A375 xenograft model in nude mice.
- 1 June 2005
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 48 (13) , 4208-4211
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities
A series of 1-acyl-1H-[1,2,4]triazole-3,5-diamine analogues were synthesized as cyclin-dependent kinase (CDK) inhibitors. These compounds showed potent and selective CDK1 and CDK2 inhibitory activities and inhibited in vitro cellular proliferation in various human tumor cells. Representative compound 3b demonstrated in vivo efficacy in a human melanoma A375 xenograft model in nude mice.
- 1 May 2005
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (9) , 2221-2224
3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation
- 1 May 2005
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (9) , 2221-2224
3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation