Luis Octávio Regasini
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Luis Octávio Regasini has a total of 21 co-authors. Here are the top co-authors by number of shared publications:
- Vanderlan da Silva Bolzani
Universidade Estadual Paulista
2 shared publications Ana Marisa Fusco-Almeida
Univ Estadual Paulista, Dept Anal Clin & Toxicol, Fac Ciencias Farmaceut, BR-14801902 Araraquara, SP, Brazil
1 shared publicationDulce Helena Siqueira Siva
Univ Estadual Paulista, Inst Quim, Dept Quim Organ, BR-14800900 Araraquara, SP, Brazil
1 shared publication- Elaine Monteiro Cardoso-Lopes
Section of Plant Physiology and Biochemistry, Institute of Botany, Box 3005, 01061-970, São Paulo, SP, Brazil
1 shared publication - Eliezer Jesus Barreiro
Universidade Federal do Rio de Janeiro
1 shared publication - Fernando Cotinguiba
Instituto de Pesquisas de Produtos Naturais Walter Mors (IPPN), Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro (UFRJ), Avenida Carlos Chagas Filho, 373, Bloco H, Rio de Janeiro 21941-599, Brazil
1 shared publication
Latest Publications
- Open Access
Alkaloids from Stems of Esenbeckia leiocarpa Engl. (Rutaceae) as Potential Treatment for Alzheimer Disease
Esenbeckia leiocarpa Engl. (Rutaceae), popularly known as guarantã, goiabeira, is a native tree from Brazil. Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, leptomerine, kokusaginine, skimmianine, maculine and flindersiamine. All isolated compounds were tested for acetyl cholinesterase inhibition, in vitro and displayed anticholinesterasic activity. The alkaloid leptomerine showed the highest activity (IC50 = 2.5 mM), similar to that of the reference compound galanthamine (IC50 = 1.7 mM). The results showed for the first time the presence of alkaloids leptomerine and skimmianine in E. leiocarpa (Engl.) with potent anticholinesterasic activity.
Open AccessAlkaloids from Stems of Esenbeckia leiocarpa Engl. (Rutaceae) as Potential Treatment for Alzheimer Disease
Esenbeckia leiocarpa Engl. (Rutaceae), popularly known as guarantã, goiabeira, is a native tree from Brazil. Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, leptomerine, kokusaginine, skimmianine, maculine and flindersiamine. All isolated compounds were tested for acetyl cholinesterase inhibition, in vitro and displayed anticholinesterasic activity. The alkaloid leptomerine showed the highest activity (IC50 = 2.5 mM), similar to that of the reference compound galanthamine (IC50 = 1.7 mM). The results showed for the first time the presence of alkaloids leptomerine and skimmianine in E. leiocarpa (Engl.) with potent anticholinesterasic activity.
- Open Access
- 1 November 2010
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 20 (5) , 706-711
Antimicrobial activity of Pterogyne nitens Tul., Fabaceae, against opportunistic fungi
- 1 November 2010
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 20 (5) , 706-711
Open AccessAntimicrobial activity of Pterogyne nitens Tul., Fabaceae, against opportunistic fungi
- Open Access
- 1 March 2009
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 19 (1b) , 199-203
Trypanocidal activity of Piper arboreum and Piper tuberculatum (Piperaceae)
- 1 March 2009
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 19 (1b) , 199-203
Open AccessTrypanocidal activity of Piper arboreum and Piper tuberculatum (Piperaceae)