Sebastian T. Schindera
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Sebastian T. Schindera has a total of 86 co-authors. Here are the top co-authors by number of shared publications:
Zsolt Szucs-Farkas
Institute of Radiology, Hospital Centre of Biel, Biel, Switzerland
10 shared publicationsDaniele Marin
Department of Radiology, Duke University Medical Center, Durham, NC, USA
5 shared publicationsPeter Vock
From the *University Institute of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, University of Bern, Bern, Switzerland; †Engineering and Information Technology, Bern University of Applied Sciences, Biel/Bienne, Switzerland; and ‡Department of Radiology, Duke University Medical Center, Durham, NC
5 shared publicationsAndré Euler
Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, CH-4031, Basel, Switzerland
3 shared publicationsBram Stieltjes
Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, CH-4031, Basel, Switzerland
3 shared publicationsCaroline Zaehringer
Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, CH-4031, Basel, Switzerland
3 shared publications
Latest Publications
- 19 February 2018
- Published by Springer Nature in European Radiology
- Vol. 28 (8) , 3405-3412
Comparison of image quality and radiation dose between split-filter dual-energy images and single-energy images in single-source abdominal CT
To compare image quality and radiation dose of abdominal split-filter dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT (SECT) with automatic tube voltage selection (ATVS).
- 19 February 2018
- Published by Springer Nature in European Radiology
- Vol. 28 (8) , 3405-3412
Comparison of image quality and radiation dose between split-filter dual-energy images and single-energy images in single-source abdominal CT
To compare image quality and radiation dose of abdominal split-filter dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT (SECT) with automatic tube voltage selection (ATVS).
- 1 December 2017
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 209 (6) , 1302-1307
Transatlantic Comparison of CT Radiation Doses in the Era of Radiation Dose–Tracking Software
OBJECTIVE. The purpose of this study is to compare diagnostic reference levels from a local European CT dose registry, using radiation-tracking software from a large patient sample, with preexisting European and North American diagnostic reference levels. MATERIALS AND METHODS. Data (n = 43,761 CT scans obtained over the course of 2 years) for the European local CT dose registry were obtained from eight CT scanners at six institutions. Means, medians, and interquartile ranges of volumetric CT dose index (CTDIvol), dose-length product (DLP), size-specific dose estimate, and effective dose values for CT examinations of the head, paranasal sinuses, thorax, pulmonary angiogram, abdomen-pelvis, renal-colic, thorax-abdomen-pelvis, and thoracoabdominal angiogram were obtained using radiation-tracking software. Metrics from this registry were compared with diagnostic reference levels from Canada and California (published in 2015), the American College of Radiology (ACR) dose index registry (2015), and national di...
- 1 December 2017
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 209 (6) , 1302-1307
Transatlantic Comparison of CT Radiation Doses in the Era of Radiation Dose–Tracking Software
OBJECTIVE. The purpose of this study is to compare diagnostic reference levels from a local European CT dose registry, using radiation-tracking software from a large patient sample, with preexisting European and North American diagnostic reference levels. MATERIALS AND METHODS. Data (n = 43,761 CT scans obtained over the course of 2 years) for the European local CT dose registry were obtained from eight CT scanners at six institutions. Means, medians, and interquartile ranges of volumetric CT dose index (CTDIvol), dose-length product (DLP), size-specific dose estimate, and effective dose values for CT examinations of the head, paranasal sinuses, thorax, pulmonary angiogram, abdomen-pelvis, renal-colic, thorax-abdomen-pelvis, and thoracoabdominal angiogram were obtained using radiation-tracking software. Metrics from this registry were compared with diagnostic reference levels from Canada and California (published in 2015), the American College of Radiology (ACR) dose index registry (2015), and national di...
- 29 September 2017
- Published by Springer Nature in European Radiology
- Vol. 27 (12) , 5260
Erratum to: Impact of model-based iterative reconstruction on low-contrast lesion detection and image quality in abdominal CT: a 12-reader-based comparative phantom study with filtered back projection at different tube voltages
- 29 September 2017
- Published by Springer Nature in European Radiology
- Vol. 27 (12) , 5260
Erratum to: Impact of model-based iterative reconstruction on low-contrast lesion detection and image quality in abdominal CT: a 12-reader-based comparative phantom study with filtered back projection at different tube voltages
- 3 April 2017
- Published by Springer Nature in European Radiology
- Vol. 27 (12) , 5252-5259
Impact of model-based iterative reconstruction on low-contrast lesion detection and image quality in abdominal CT: a 12-reader-based comparative phantom study with filtered back projection at different tube voltages
To evaluate the impact of model-based iterative reconstruction (MBIR) on image quality and low-contrast lesion detection compared with filtered back projection (FBP) in abdominal computed tomography (CT) of simulated medium and large patients at different tube voltages.
- 3 April 2017
- Published by Springer Nature in European Radiology
- Vol. 27 (12) , 5252-5259
Impact of model-based iterative reconstruction on low-contrast lesion detection and image quality in abdominal CT: a 12-reader-based comparative phantom study with filtered back projection at different tube voltages
To evaluate the impact of model-based iterative reconstruction (MBIR) on image quality and low-contrast lesion detection compared with filtered back projection (FBP) in abdominal computed tomography (CT) of simulated medium and large patients at different tube voltages.
- 1 September 2016
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 280 (3) , 663-673
CT Radiation Dose Management: A Comprehensive Optimization Process for Improving Patient Safety
We define CT dose management as the organization and coordination of activities to review and optimize radiation doses to ensure patient safety. Rising concerns of radiation exposure from computed tomography have caused various advances in dose reduction technologies. While proper justification and optimization of scans has been the main focus to address increasing doses, the value of dose management has been largely overlooked. The purpose of this article is to explain the importance of dose management, provide an overview of the available options for dose tracking, and discuss the importance of a dedicated dose team. The authors also describe how a digital radiation tracking software can be used for analyzing the big data on doses for auditing patient safety, scanner utilization, and productivity, all of which have enormous personal and institutional implications.© RSNA, 2016
- 1 September 2016
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 280 (3) , 663-673
CT Radiation Dose Management: A Comprehensive Optimization Process for Improving Patient Safety
We define CT dose management as the organization and coordination of activities to review and optimize radiation doses to ensure patient safety. Rising concerns of radiation exposure from computed tomography have caused various advances in dose reduction technologies. While proper justification and optimization of scans has been the main focus to address increasing doses, the value of dose management has been largely overlooked. The purpose of this article is to explain the importance of dose management, provide an overview of the available options for dose tracking, and discuss the importance of a dedicated dose team. The authors also describe how a digital radiation tracking software can be used for analyzing the big data on doses for auditing patient safety, scanner utilization, and productivity, all of which have enormous personal and institutional implications.© RSNA, 2016
- 15 October 2014
- Published by Springer Nature in European Radiology
- Vol. 25 (3) , 687-693
Assessment of image quality and low-contrast detectability in abdominal CT of obese patients: comparison of a novel integrated circuit with a conventional discrete circuit detector at different tube voltages
To compare image quality and low-contrast detectability of an integrated circuit (IC) detector in abdominal CT of obese patients with conventional detector technology at low tube voltages. A liver phantom with 45 lesions was placed in a water container to mimic an obese patient and examined on two different CT systems at 80, 100 and 120 kVp. The systems were equipped with either the IC or conventional detector. Image noise was measured, and the contrast-to-noise-ratio (CNR) was calculated. Low-contrast detectability was assessed independently by three radiologists. Radiation dose was estimated by the volume CT dose index (CTDIvol). The image noise was significantly lower, and the CNR was significantly higher with the IC detector at 80, 100 and 120 kVp, respectively (P = 0.023). The IC detector resulted in an increased lesion detection rate at 80 kVp (38.1 % vs. 17.2 %) and 100 kVp (57.0 % vs. 41.0 %). There was no difference in the detection rate between the IC detector at 100 kVp and the conventional detector at 120 kVp (57.0 % vs. 62.2 %). The CTDIvol at 80, 100 and 120 kVp measured 4.5–5.2, 7.3–7.9 and 9.8–10.2 mGy, respectively. The IC detector at 100 kVp resulted in similar low-contrast detectability compared to the conventional detector with a 120-kVp protocol at a radiation dose reduction of 37 %. • An integrated circuit (IC) detector significantly improves the quantitative image quality • The IC detector results in a significant improvement of low-contrast detectability • Reduction of tube voltage to 100 kVp is feasible in obese patients • The IC detector holds great promise for improving patient safety
- 15 October 2014
- Published by Springer Nature in European Radiology
- Vol. 25 (3) , 687-693
Assessment of image quality and low-contrast detectability in abdominal CT of obese patients: comparison of a novel integrated circuit with a conventional discrete circuit detector at different tube voltages
To compare image quality and low-contrast detectability of an integrated circuit (IC) detector in abdominal CT of obese patients with conventional detector technology at low tube voltages. A liver phantom with 45 lesions was placed in a water container to mimic an obese patient and examined on two different CT systems at 80, 100 and 120 kVp. The systems were equipped with either the IC or conventional detector. Image noise was measured, and the contrast-to-noise-ratio (CNR) was calculated. Low-contrast detectability was assessed independently by three radiologists. Radiation dose was estimated by the volume CT dose index (CTDIvol). The image noise was significantly lower, and the CNR was significantly higher with the IC detector at 80, 100 and 120 kVp, respectively (P = 0.023). The IC detector resulted in an increased lesion detection rate at 80 kVp (38.1 % vs. 17.2 %) and 100 kVp (57.0 % vs. 41.0 %). There was no difference in the detection rate between the IC detector at 100 kVp and the conventional detector at 120 kVp (57.0 % vs. 62.2 %). The CTDIvol at 80, 100 and 120 kVp measured 4.5–5.2, 7.3–7.9 and 9.8–10.2 mGy, respectively. The IC detector at 100 kVp resulted in similar low-contrast detectability compared to the conventional detector with a 120-kVp protocol at a radiation dose reduction of 37 %. • An integrated circuit (IC) detector significantly improves the quantitative image quality • The IC detector results in a significant improvement of low-contrast detectability • Reduction of tube voltage to 100 kVp is feasible in obese patients • The IC detector holds great promise for improving patient safety
- 1 November 2013
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 269 (2) , 511-518
Iterative Reconstruction Algorithm for CT: Can Radiation Dose Be Decreased While Low-Contrast Detectability Is Preserved?
- 1 November 2013
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 269 (2) , 511-518
Iterative Reconstruction Algorithm for CT: Can Radiation Dose Be Decreased While Low-Contrast Detectability Is Preserved?
- 1 April 2013
- Published by Elsevier in Journal of Forensic Radiology and Imaging
- Vol. 1 (2) , 51-55
The Forensic Reference Phantom—a new tool for quality assurance of attenuation measurements in forensic radiology
- 1 April 2013
- Published by Elsevier in Journal of Forensic Radiology and Imaging
- Vol. 1 (2) , 51-55
The Forensic Reference Phantom—a new tool for quality assurance of attenuation measurements in forensic radiology
- 1 February 2013
- Published by Elsevier in Clinical Radiology
- Vol. 68 (2) , e79-e86
Effect of automatic tube voltage selection on image quality and radiation dose in abdominal CT angiography of various body sizes: A phantom study
- 1 February 2013
- Published by Elsevier in Clinical Radiology
- Vol. 68 (2) , e79-e86
Effect of automatic tube voltage selection on image quality and radiation dose in abdominal CT angiography of various body sizes: A phantom study
- 1 March 2012
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 47 (3) , 197-201
Effect of Tumor Size and Tumor-to-Liver Contrast of Hypovascular Liver Tumors on the Diagnostic Performance of Hepatic CT Imaging
Objective: To assess the effect of tumor size and tumor-to-liver contrast of simulated hypovascular liver tumors on the diagnostic accuracy of hepatic computed tomography (CT). Materials and Methods: This retrospective study was approved by the institutional review board, and informed consent was waived. A total of 153 simulated hypovascular liver tumors were embedded in 70 hepatic CT data sets that were acquired during the portal venous phase. The simulated tumors had 3 different diameters (6, 10, and 14 mm) and 3 different tumor-to-liver contrast values (20, 35, and 50 HU). There were also 30 hepatic CT data sets without liver tumors. Three radiologists independently performed tumor detection on the randomized 100 hepatic CT data sets. Results: The lowest sensitivity was obtained for the 6-mm tumors with a tumor-to-liver contrast of 20 HU (4.1%), and the highest sensitivity was obtained for the 10- and 14-mm tumors with a tumor-to-liver contrast of 50 HU (100%). Increasing the contrast from 20 to 35 to 50 HU in the 6-mm tumors yielded a significant increase in sensitivity (4.1%, 48.8%, and 92.4%, respectively; P < 0.0001). The sensitivity for the 10- and 14-mm tumors also increased significantly as the tumor-to-liver contrast value increased from 20 to 35 HU (P < 0.01). However, no significant increase in sensitivity was seen for the 10- and 14-mm tumors as the tumor-to-liver contrast values increased from 35 to 50 HU (P = 0.733 and P = 1.0, respectively). Conclusions: Increasing the tumor-to-liver contrast from 20 to 35 HU results in a significant increase in the detection of hypovascular liver tumors ranging from 6 to 14 mm in diameter. Optimization of the tumor-to-liver contrast is necessary for improved detection of hypovascular liver tumors.
- 1 March 2012
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 47 (3) , 197-201
Effect of Tumor Size and Tumor-to-Liver Contrast of Hypovascular Liver Tumors on the Diagnostic Performance of Hepatic CT Imaging
Objective: To assess the effect of tumor size and tumor-to-liver contrast of simulated hypovascular liver tumors on the diagnostic accuracy of hepatic computed tomography (CT). Materials and Methods: This retrospective study was approved by the institutional review board, and informed consent was waived. A total of 153 simulated hypovascular liver tumors were embedded in 70 hepatic CT data sets that were acquired during the portal venous phase. The simulated tumors had 3 different diameters (6, 10, and 14 mm) and 3 different tumor-to-liver contrast values (20, 35, and 50 HU). There were also 30 hepatic CT data sets without liver tumors. Three radiologists independently performed tumor detection on the randomized 100 hepatic CT data sets. Results: The lowest sensitivity was obtained for the 6-mm tumors with a tumor-to-liver contrast of 20 HU (4.1%), and the highest sensitivity was obtained for the 10- and 14-mm tumors with a tumor-to-liver contrast of 50 HU (100%). Increasing the contrast from 20 to 35 to 50 HU in the 6-mm tumors yielded a significant increase in sensitivity (4.1%, 48.8%, and 92.4%, respectively; P < 0.0001). The sensitivity for the 10- and 14-mm tumors also increased significantly as the tumor-to-liver contrast value increased from 20 to 35 HU (P < 0.01). However, no significant increase in sensitivity was seen for the 10- and 14-mm tumors as the tumor-to-liver contrast values increased from 35 to 50 HU (P = 0.733 and P = 1.0, respectively). Conclusions: Increasing the tumor-to-liver contrast from 20 to 35 HU results in a significant increase in the detection of hypovascular liver tumors ranging from 6 to 14 mm in diameter. Optimization of the tumor-to-liver contrast is necessary for improved detection of hypovascular liver tumors.