Codruta Nemet

Our professional interest in human trichinellosis evolution lies for a period of 30 years (1983-2013). In this study we have included 1112 cases of human trichinellosis recorded in that period of time. The aim of the study was: the symptoms and clinical signs correlated with the results of laboratory tests and epidemiological investigations could lead the physician to suspect the trichinellosis. Thus would shorten the patient route by various medical specialties until diagnosing the trichinellosis and would hasten the establishment of antiparasitic treatment. Severe symptoms did not hasten accurate diagnosis of trichinellosis owing to frequent misdiagnosis. High numbers of eosinophil cells was found consistently in all forms of the disease, which confirms the value of this investigation in the diagnosis of trichinellosis. We emphasize the importance of performing dynamic eosinophilia and dysproteinemia tests for the diagnosis of the disease and its follow-up evolution.

The history of cholera, a specific infection caused by Vibrio Cholerae, starts in ancient times. The sixth pandemic that began in 1899 and lasted until 1923, started in India and came to Eastern Europe through Russia. The expansion of the epidemic in the Balkans was facilitated both by the 2 Balkan Wars and the First World War. Romania, as a participant in these wars was affected by cholera, which was especially common among the army during the Balkan War. If the original source of the cholera issue is still controversial, both Romanians and Bulgarians accusing each other of being the basis of the outbreaks south of the Danube, it is widely recognized that the extent of the disease was facilitated by the sanitary conditions of food preparation and drinking water sources among both Romanian soldiers and in the civilian population. Under these conditions, in addition to numerous measures against cholera taken by the Ministry of War, Prof. I. Cantacuzino successfully experiments outbreak vaccination for the first time in the world with a vaccine prepared by himself and his collaborators. The vaccine containing 25 breeds of vibriones was a success in terms of rapid development of a preparation, the application of which was achieved through a quick campaign and proved extremely efficient, imposing the Romanian method as an effective way to combat a disease in full outbreak.