Magdalena Ziółkowska

The epidemiological data concerning the rare group of tumors derived from salivary glands recorded in the National Cancer Registry is insufficient because it records only malignant salivary glands tumors. The epidemiological and clinical characteristics of 699 patients with salivary glands tumors (n=705). The data were retrieved from ENT Department District Hospital in Kielce (01.09.1989-28.02.2001) and from Department of Otolaryngology Head and Neck Surgery Holy Cross Cancer Centre in Kielce (01.03.2001-31.12.2008). In the analyzed group of 699 patients with 705 salivary glands tumors women predominated, consisting 54,2% of all group. The average age in group of malignant tumors was higher than in nonmalignant group. The risk of malignant neoplasms development increased with patient age. In the analyzed group of 705 salivary glands tumors the nonmalignant neoplasms dominated-78,3%. Out of all cases, 547 (77,6%) were localized in the parotid gland, 80 (11,3%) in submandibular gland and 78 (11,1%) in minor salivary glands. Nonmalignant tumors were more frequent in the parotid gland (82,8%) and submandibular gland (71,3%), whereas in minor salivary glands nonmalignant and malignant neoplasms the occurrence was nearly the same. In general-the smaller the salivary gland, the risk of development malignant tumors was higher. In group of nonmalignant salivary gland tumors two histopathological types dominated - pleomorphic adenoma and Warthin's tumor, which comprised 91,8% of the whole group. In the group of 153 malignant salivary gland tumors the most common histopathology were - adenoid cystic carcinoma, mucoepidermoid carcinoma and adenocarcinoma. In the analyzed period of 20 years' time, the incidence of salivary glands tumors increased with high siginificance, both for nonmalignant, as well malignant tumors.

Not only primary malignancies but also metastatic tumors may be found within the parotid gland. Epidemiological and clinical characteristic, and preliminary assessment of treatment results. The retrospective analysis of 95 cases with metastatic tumors to the parotid gland, selected from the material of H&N Surg. Dept of Holy Cross Cancer Center in Kielce – Poland (2001–2011), with the analysis of age, sex, localization and histopathology of primary tumor, stage according to O’Brien classification, diagnostic methods and treatment modalities, and analysis of 3 and 5 years survival. Studied group consits of 95 patients (56 M, 39 F), in the age ranging from 31 to 97 years (mean 74.6). The most common primary localization of metastatic tumor was skin of the head and neck (Squamous Cell Ca – 53.7%; Malignant Melanoma 28.4%). 81% of patients underwent radical therapy intentionally – mostly combined surgery and radiotherapy. 19.0% of patients received symptomatic and palliative treatment only. In the group with 3 and 5 years of observation accordingly, 51.7% and 34.0% total survival was achieved.