Bruno Imthurn
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Bruno Imthurn has a total of 28 co-authors. Here are the top co-authors by number of shared publications:
- Ervin Macas
Division of Reproductive Endocrinology, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland
3 shared publications - Daniel Fink
Universitätsspital Zürich
2 shared publications - David Scheiner
University of Zurich, Zurich, Switzerland; Department of Gynecology, University Hospital of Zurich, Zurich, Switzerland; Practice Blasenzentrum AG, Zurich, Switzerland
2 shared publications - Patrick Imesch
Department of Gynecology, University Hospital Zurich, Zurich, Switzerland
2 shared publications Anita Rauch
University of Zürich
1 shared publicationArter Klug
Genetica AG Zurich Switzerland
1 shared publication
Latest Publications
- 28 November 2019
- Published by Springer Nature
- p. 627-636
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- 28 November 2019
- Published by Springer Nature
- p. 627-636
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- 28 August 2019
- Published by Springer Nature in Gynäkologische Endokrinologie
- Vol. 17 (3) , 127-128
Gerinnung und Reproduktion
- 28 August 2019
- Published by Springer Nature in Gynäkologische Endokrinologie
- Vol. 17 (3) , 127-128
Gerinnung und Reproduktion
- 22 November 2018
- Published by Springer Nature
- p. 1-11
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- 22 November 2018
- Published by Springer Nature
- p. 1-11
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- Open Access
- 26 September 2016
- Published by Springer Nature in Journal of Ovarian Research
- Vol. 9 (1) , 59
Comparison of quartz vials with polypropylene vials for rapid cryopreservation of human ovarian tissue
Because higher survival of follicles during the freezing/thawing procedure improves the quality of cryopreserved tissue reimplanted after oncological therapies, defining an optimal method for human ovarian tissue cryopreservation remains a major issue in this field. One option to improve the cryopreservation procedure is to use better materials, i.e., vials with better conductivity. The aim of this study was to compare polypropylene (PP) with quartz vials. Between September 2012 and January 2013, eight patients were recruited. The ovarian cortex was cut into 3 slices, assigned randomly to a fresh and a cryopreserved group in PP (method B) or quartz vials (method C). Histological and immunohistochemical (IHC) analysis were used. For IHC three antibodies were analyzed: Ki67 (proliferation index), Bcl2 (anti apoptotic index) and Hsp70 (stress index). The majority of GCs showed positive staining for Bcl2 in both cryopreservation device, with higher expression in group C than in group B. Oocytes and their nuclei showed intense positive staining for ki67 in both methods B and C, and also a patch positive stromal cells staining for Ki67. Expression of hsp70 was not increased after cryopreservation. Cryopreservation using quartz vials led to larger numbers of good follicles while maintaining consistent preservation for stromal cells and vessels.
- 26 September 2016
- Published by Springer Nature in Journal of Ovarian Research
- Vol. 9 (1) , 59
Open AccessComparison of quartz vials with polypropylene vials for rapid cryopreservation of human ovarian tissue
Because higher survival of follicles during the freezing/thawing procedure improves the quality of cryopreserved tissue reimplanted after oncological therapies, defining an optimal method for human ovarian tissue cryopreservation remains a major issue in this field. One option to improve the cryopreservation procedure is to use better materials, i.e., vials with better conductivity. The aim of this study was to compare polypropylene (PP) with quartz vials. Between September 2012 and January 2013, eight patients were recruited. The ovarian cortex was cut into 3 slices, assigned randomly to a fresh and a cryopreserved group in PP (method B) or quartz vials (method C). Histological and immunohistochemical (IHC) analysis were used. For IHC three antibodies were analyzed: Ki67 (proliferation index), Bcl2 (anti apoptotic index) and Hsp70 (stress index). The majority of GCs showed positive staining for Bcl2 in both cryopreservation device, with higher expression in group C than in group B. Oocytes and their nuclei showed intense positive staining for ki67 in both methods B and C, and also a patch positive stromal cells staining for Ki67. Expression of hsp70 was not increased after cryopreservation. Cryopreservation using quartz vials led to larger numbers of good follicles while maintaining consistent preservation for stromal cells and vessels.
- 1 January 2015
- Published by Springer Nature
- p. 103-121
Polar Body Diagnosis (PBD): An Alternative and Supplement to Preimplantation Diagnosis for Single Embryo Transfer
- 1 January 2015
- Published by Springer Nature
- p. 103-121
Polar Body Diagnosis (PBD): An Alternative and Supplement to Preimplantation Diagnosis for Single Embryo Transfer
- Open Access
- 18 April 2013
- Published by Springer Nature in Journal of Ovarian Research
- Vol. 6 (1) , 30
Developmental potential of human oocytes matured in vitro followed by vitrification and activation
Oocyte in vitro maturation (IVM) and cryopreservation at the time of routine ovarian tissue freezing may be offered to cancer patients as an additional option for fertility preservation. This study aimed to investigate the developmental capacity of oocytes isolated from unstimulated ovaries.
- 18 April 2013
- Published by Springer Nature in Journal of Ovarian Research
- Vol. 6 (1) , 30
Open AccessDevelopmental potential of human oocytes matured in vitro followed by vitrification and activation
Oocyte in vitro maturation (IVM) and cryopreservation at the time of routine ovarian tissue freezing may be offered to cancer patients as an additional option for fertility preservation. This study aimed to investigate the developmental capacity of oocytes isolated from unstimulated ovaries.
- 1 January 2013
- Published by Springer Nature
- p. 621-629
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- 1 January 2013
- Published by Springer Nature
- p. 621-629
Rechtliche Regelung der Reproduktionsmedizin in der Schweiz
- 30 June 2006
- Published by Elsevier in Fertility and Sterility
- Vol. 85 (6) , 1753-1760
Numerical chromosome anomalies detected in paternally derived pronuclei of tripronuclear zygotes after intracytoplasmic sperm injection
- 30 June 2006
- Published by Elsevier in Fertility and Sterility
- Vol. 85 (6) , 1753-1760
Numerical chromosome anomalies detected in paternally derived pronuclei of tripronuclear zygotes after intracytoplasmic sperm injection
- Open Access
- 1 May 2004
- Published by SMW Supporting Association in Swiss Medical Weekly
- Vol. 134 (1718) , 254-258
Preimplantation diagnosis in Switzerland - birth of a healthy child after polar body biopsy
In Switzerland preimplantation genetic diagnosis is limited by law to polar body biopsy (PBB). The indications for PBB include unexplained recurrent miscarriage and improvement of the outcome of in vitro fertilisation (IVF) cycles in women at an advanced reproductive age. In this article we report the first birth of a healthy child after polar body biopsy in Switzerland in a case of unexplained miscarriage after IVF.
- 1 May 2004
- Published by SMW Supporting Association in Swiss Medical Weekly
- Vol. 134 (1718) , 254-258
Open AccessPreimplantation diagnosis in Switzerland - birth of a healthy child after polar body biopsy
In Switzerland preimplantation genetic diagnosis is limited by law to polar body biopsy (PBB). The indications for PBB include unexplained recurrent miscarriage and improvement of the outcome of in vitro fertilisation (IVF) cycles in women at an advanced reproductive age. In this article we report the first birth of a healthy child after polar body biopsy in Switzerland in a case of unexplained miscarriage after IVF.