Behairi Nassima
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Behairi Nassima has a total of 11 co-authors. Here are the top co-authors by number of shared publications:
Belarbi Soreya
1 shared publicationBelkhelfa Mourad
1 shared publication- Chafia Touil-Boukoffa
Team "Cytokines and NO synthases: Immunity and pathogenesis", LBCM, FSB, USTHB, Algiers, Algeria
1 shared publication - Hamida Mesbah-Amroun
Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, Algiers, Algeria
1 shared publication - Hayet Rafa
Laboratory of Cellular and Molecular Biology, Cytokines and NO Synthases-Immunity and Pathogenesis, Faculty of Biological Science, University of Sciences and Technology (USTHB), Algiers, Algeria
1 shared publication - Mourad Belkhelfa
Cytokines and NO-Synthases, Immunity and Pathogenesis Team, Laboratory of Cellular and Molecular Biology, Faculty of Biological Science, University of Sciences and Technology Houari Boumediene, Algiers, Algeria
1 shared publication
Latest Publications
- 1 November 2016
- Published by Elsevier in Journal of Neuroimmunology
- Vol. 300, 21-29
All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats
- 1 November 2016
- Published by Elsevier in Journal of Neuroimmunology
- Vol. 300, 21-29
All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats
- Open Access
- 1 January 2014
- Published by Frontiers Media SA in Frontiers in Immunology
- Vol. 5
Modulation of nitric oxide production by peripheral blood mononuclear cells of Algerian patients with Alzheimer’s disease using vitamin A and vitamin D; a therapeutic approach
Introduction: Alzheimer’s disease (AD) constitutes a progressive neurodegenerative disorder and the main cause of dementia in the elderly. A growing body of evidence has associated neuroinflammation and oxidative stress to the onset and the progression of the pathology. Inducible Nitric Oxide Synthase (iNOS) and its product (NO) have been involved in AD pathogenesis. Antioxidant and immune-modulatory properties of vitamin A and vitamin D have been shown in several immune disorders. In our current study, we investigate the modulatory effects of both vitamin A and vitamin D on nitric oxide production in Algerian patients with Alzheimer’s disease. Materials and methods: Peripheral Blood Mononuclear Cells (PBMCs) were isolated from 15 Algerian patients with Alzheimer’s disease. Ex vivo PBMCs cultures were conducted in presence of vitamin A or vitamin D in RPMI 1640 medium for 24 hours. Nitric oxide production in culture supernatants was assessed using modified Griess method. Results: Both vitamin A and vitamin D down-modulated the nitric oxide production by PBMCs of Alzheimer’s disease patients. Interestingly, the vitamin D effect was more important compared to vitamin A one. Discussion/Conclusion: Our reports suggest that modulatory effects of vitamin A and vitamin D on nitric oxide production can be used as a promising therapeutic approach in Alzheimer’s disease.
- 1 January 2014
- Published by Frontiers Media SA in Frontiers in Immunology
- Vol. 5
Open AccessModulation of nitric oxide production by peripheral blood mononuclear cells of Algerian patients with Alzheimer’s disease using vitamin A and vitamin D; a therapeutic approach
Introduction: Alzheimer’s disease (AD) constitutes a progressive neurodegenerative disorder and the main cause of dementia in the elderly. A growing body of evidence has associated neuroinflammation and oxidative stress to the onset and the progression of the pathology. Inducible Nitric Oxide Synthase (iNOS) and its product (NO) have been involved in AD pathogenesis. Antioxidant and immune-modulatory properties of vitamin A and vitamin D have been shown in several immune disorders. In our current study, we investigate the modulatory effects of both vitamin A and vitamin D on nitric oxide production in Algerian patients with Alzheimer’s disease. Materials and methods: Peripheral Blood Mononuclear Cells (PBMCs) were isolated from 15 Algerian patients with Alzheimer’s disease. Ex vivo PBMCs cultures were conducted in presence of vitamin A or vitamin D in RPMI 1640 medium for 24 hours. Nitric oxide production in culture supernatants was assessed using modified Griess method. Results: Both vitamin A and vitamin D down-modulated the nitric oxide production by PBMCs of Alzheimer’s disease patients. Interestingly, the vitamin D effect was more important compared to vitamin A one. Discussion/Conclusion: Our reports suggest that modulatory effects of vitamin A and vitamin D on nitric oxide production can be used as a promising therapeutic approach in Alzheimer’s disease.