Rosa Ramírez Bartutis

Rosa Ramírez Bartutis

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

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Rosa Ramírez Bartutis has a total of 8 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Domain III of the envelope protein as a dengue vaccine target

    by Maria G Guzman, Lisset Hermida, Lidice Bernardo, Rosa Ramirez, Gerardo Guillén

    A dengue vaccine should induce long-lasting, simultaneous protection to the four dengue viruses while avoiding the immune enhancement of viral infection. Domain III of the dengue envelope protein h...


    • 1 November 2007
      • Vol. 57  (3) , 175-9

    [Study of the genetical stability of the system of expression of protein E of dengue virus 4 in methyltrophic yeast Pichia pastoris].

    by Rosa Ramírez Bartutis, Mayra Muné Jiménez, Manuel Mansur, Yudira Soto Brito, Tamara Pimentel

    The plasmidic stability of methyltrophic yeast Pichia pastoris expressing the recombinant protein E of dengue virus 4 was analyzed. To this end, the number of generations from the growth process in petri plaque to the propagation in zaranda was estimated, as well as the fermentation process. Besides, in the selected colonies the integration pattern was determined by Dot-Blot and neuclotide sequence of the gene E of dengue virus 4. This study allowed to prove the conservation and integrity of the aminoacid sequence of protein E, despite the genetic changes produced by molecular yeast mechanisms. On the other hand, it was also part of the control and checking of the primary bank of yeast cells that contains the gene of interest used at present in the process of expression of protein E of dengue virus 4.