MCMathew Jose Chakaramakkil

Mathew Jose Chakaramakkil

*This is an algorithmically generated author record based on publicly available information.

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Mathew Jose Chakaramakkil has a total of 2 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • ECMO in cardiogenic shock and bridge to heart transplant

    by Mathew Jose Chakaramakkil, Cumaraswamy Sivathasan

    Purpose The aim of this review is to discuss the role of extracorporeal membrane oxygenation (ECMO) in cardiogenic shock and its use to bridge patients to heart transplantation. Methods and results Consideration of published literature reveals indications for ECMO in cardiogenic shock and tools for patient selection, adequate evidence of its efficacy, its advantages when compared with other temporary mechanical circulatory support devices and details of its use as a bridge to decision, bridge to recovery, bridge to bridge (durable ventricular assist device) and bridge to heart transplant. Conclusion ECMO is invaluable in treating patients with medically refractory profound cardiogenic shock and allows for cardiac recovery or planning for permanent heart replacement treatments.


  • ECMO and Short-term Support for Cardiogenic Shock in Heart Failure

    by Mathew Jose Chakaramakkil, Cumaraswamy Sivathasan

    Purpose of Review This review aims to discuss the role of ECMO in the treatment of cardiogenic shock in heart failure. Recent Findings Trials done previously have shown that IABP does not improve survival in cardiogenic shock compared to medical treatment, and that neither Impella 2.5 nor TandemHeart improves survival compared to IABP. The “IMPRESS in severe shock” trial compared Impella CP with IABP and found no difference in survival. A meta-analysis of cohort studies comparing ECMO with IABP showed 33% improved 30-day survival with ECMO (risk difference 33%; 95% CI 14–52%; p = 0.0008; NNT 3). Summary ECMO is indicated in medically refractory cardiogenic shock. ECMO can be considered in cardiogenic shock patients with estimated mortality of more than 50%. ECMO is probably the MCS of choice in cardiogenic shock with; biventricular failure, respiratory failure, life-threatening arrhythmias and cardiac arrest.