Joana Maria Ramis
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Joana Maria Ramis has a total of 3 co-authors. Here are the top co-authors by number of shared publications:
- Maria Antonia Llopis-Grimalt
University College Cork
1 shared publication - Maria Del Mar Ferrà-Cañellas
Health Research Institute of the Balearic Islands (IdISBa) , Palma , Spain
1 shared publication - Marta Monjo
Group of Cell Therapy and Tissue Engineering, Research Institute on Health Sciences (IUNICS) University of the Balearic Islands Palma de Mallorca Spain
1 shared publication
Latest Publications
- Open Access
- 22 September 2018
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 19 (10) , 2881
Tuning Nanopore Diameter of Titanium Surfaces to Improve Human Gingival Fibroblast Response
The aim of this study was to determine the optimal nanopore diameter of titanium nanostructured surfaces to improve human gingival fibroblast (hGF) response, with the purpose of promoting gingiva integration to dental implant abutments. Two TiO2 nanoporous groups with different diameters (NP-S ~48 nm and NP-B ~74 nm) were grown on Ti foils using an organic electrolyte containing fluoride by electrochemical oxidation, varying the applied voltage and the interelectrode spacing. The surfaces were characterized by scanning electron microscope (SEM), atomic force microscopy (AFM), and contact angle. The hGF were cultured onto the different surfaces, and metabolic activity, cytotoxicity, cell adhesion, and gene expression were analyzed. Bigger porous diameters (NP-B) were obtained by increasing the voltage used during anodization. To obtain the smallest diameter (NP-S), apart from lowering the voltage, a lower interelectrode spacing was needed. The greatest surface area and number of peaks was found for NP-B, despite these samples not being the roughest as defined by Ra. NP-B had a better cellular response compared to NP-S. However, these effects had a significant dependence on the cell donor. In conclusion, nanoporous groups with a diameter in the range of 74 nm induce a better hGF response, which may be beneficial for an effective soft tissue integration around the implant.
- 22 September 2018
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 19 (10) , 2881
Open AccessTuning Nanopore Diameter of Titanium Surfaces to Improve Human Gingival Fibroblast Response
The aim of this study was to determine the optimal nanopore diameter of titanium nanostructured surfaces to improve human gingival fibroblast (hGF) response, with the purpose of promoting gingiva integration to dental implant abutments. Two TiO2 nanoporous groups with different diameters (NP-S ~48 nm and NP-B ~74 nm) were grown on Ti foils using an organic electrolyte containing fluoride by electrochemical oxidation, varying the applied voltage and the interelectrode spacing. The surfaces were characterized by scanning electron microscope (SEM), atomic force microscopy (AFM), and contact angle. The hGF were cultured onto the different surfaces, and metabolic activity, cytotoxicity, cell adhesion, and gene expression were analyzed. Bigger porous diameters (NP-B) were obtained by increasing the voltage used during anodization. To obtain the smallest diameter (NP-S), apart from lowering the voltage, a lower interelectrode spacing was needed. The greatest surface area and number of peaks was found for NP-B, despite these samples not being the roughest as defined by Ra. NP-B had a better cellular response compared to NP-S. However, these effects had a significant dependence on the cell donor. In conclusion, nanoporous groups with a diameter in the range of 74 nm induce a better hGF response, which may be beneficial for an effective soft tissue integration around the implant.