Aaron D. Mazzeo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Research Interests
Aaron D. Mazzeo has a total of 147 co-authors. Here are the top co-authors by number of shared publications:
- George M. Whitesides
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138
12 shared publications Jingjin Xie
Department of Mechanical and Aerospace Engineering, Rutgers University, Piscataway 08854, New Jersey, United States
7 shared publicationsFilip Ilievski
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138; and
4 shared publications- Francois Berthiaume
Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, USA
4 shared publications Xin Chen
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138; and
4 shared publications- Xiyue Zou
Department of Mechanical and Aerospace Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, USA
4 shared publications
Latest Publications
- Open Access
- 4 October 2025
- Published by Elsevier in Biochemistry and Biophysics Reports
- Vol. 44, 102296
Antibacterial efficacy of combined atmospheric cold plasma and hydrogen peroxide treatment on a wound surrogate
- 4 October 2025
- Published by Elsevier in Biochemistry and Biophysics Reports
- Vol. 44, 102296
Open AccessAntibacterial efficacy of combined atmospheric cold plasma and hydrogen peroxide treatment on a wound surrogate
- Open Access
A Facile Graphene Conductive Polymer Paper Based Biosensor for Dopamine, TNF-α, and IL-6 Detection
Paper-based biosensors are a potential paradigm of sensitivity achieved via microporous spreading/microfluidics, simplicity, and affordability. In this paper, we develop decorated paper with graphene and conductive polymer (herein referred to as graphene conductive polymer paper-based sensor or GCPPS) for sensitive detection of biomolecules. Planetary mixing resulted in uniformly dispersed graphene and conductive polymer ink, which was applied to laser-cut Whatman filter paper substrates. Scanning electron microscopy and Raman spectroscopy showed strong attachment of conductive polymer-functionalized graphene to cellulose fibers. The GCPPS detected dopamine and cytokines, such as tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6) in the ranges of 12.5–400 µM, 0.005–50 ng/mL, and 2 pg/mL–2 µg/mL, respectively, using a minute sample volume of 2 µL. The electrodes showed lower detection limits (LODs) of 3.4 µM, 5.97 pg/mL, and 9.55 pg/mL for dopamine, TNF-α, and IL-6 respectively, which are promising for rapid and easy analysis for biomarkers detection. Additionally, these paper-based biosensors were highly selective (no serpin A1 detection with IL-6 antibody) and were able to detect IL-6 antigen in human serum with high sensitivity and hence, the portable, adaptable, point-of-care, quick, minute sample requirement offered by our fabricated biosensor is advantageous to healthcare applications.
Open AccessA Facile Graphene Conductive Polymer Paper Based Biosensor for Dopamine, TNF-α, and IL-6 Detection
Paper-based biosensors are a potential paradigm of sensitivity achieved via microporous spreading/microfluidics, simplicity, and affordability. In this paper, we develop decorated paper with graphene and conductive polymer (herein referred to as graphene conductive polymer paper-based sensor or GCPPS) for sensitive detection of biomolecules. Planetary mixing resulted in uniformly dispersed graphene and conductive polymer ink, which was applied to laser-cut Whatman filter paper substrates. Scanning electron microscopy and Raman spectroscopy showed strong attachment of conductive polymer-functionalized graphene to cellulose fibers. The GCPPS detected dopamine and cytokines, such as tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6) in the ranges of 12.5–400 µM, 0.005–50 ng/mL, and 2 pg/mL–2 µg/mL, respectively, using a minute sample volume of 2 µL. The electrodes showed lower detection limits (LODs) of 3.4 µM, 5.97 pg/mL, and 9.55 pg/mL for dopamine, TNF-α, and IL-6 respectively, which are promising for rapid and easy analysis for biomarkers detection. Additionally, these paper-based biosensors were highly selective (no serpin A1 detection with IL-6 antibody) and were able to detect IL-6 antigen in human serum with high sensitivity and hence, the portable, adaptable, point-of-care, quick, minute sample requirement offered by our fabricated biosensor is advantageous to healthcare applications.
- Open Access
- 12 September 2023
- Published by Wiley in Plasma Processes and Polymers
- Vol. 21 (2)
Analysis of the effects of complex electrode geometries on the energy deposition and temporally and spatially averaged electric field measurements of surface dielectric barrier discharges
Surface dielectric barrier discharges (SDBDs) have been gaining interest in part due to their scalability and flexibility of materials used, allowing larger electrodes with more complex geometries. This paper seeks to elucidate the properties of SDBD geometries utilizing differing repeated lattice structures. Voltage and current traces, optical emission spectroscopy, digital imaging, and numerical analysis are used to analyze the electrodes. Temporally and spatially averaged reduced electric fields and the total power deposited into the plasma are presented. The averaged reduced electric field is not significantly affected by increasing applied voltage, but minor variations could be observed due to the geometry of the electrode lattice structures. Finally, plasma power does not track linearly with perimeter in these more complicated lattice structures.
- 12 September 2023
- Published by Wiley in Plasma Processes and Polymers
- Vol. 21 (2)
Open AccessAnalysis of the effects of complex electrode geometries on the energy deposition and temporally and spatially averaged electric field measurements of surface dielectric barrier discharges
Surface dielectric barrier discharges (SDBDs) have been gaining interest in part due to their scalability and flexibility of materials used, allowing larger electrodes with more complex geometries. This paper seeks to elucidate the properties of SDBD geometries utilizing differing repeated lattice structures. Voltage and current traces, optical emission spectroscopy, digital imaging, and numerical analysis are used to analyze the electrodes. Temporally and spatially averaged reduced electric fields and the total power deposited into the plasma are presented. The averaged reduced electric field is not significantly affected by increasing applied voltage, but minor variations could be observed due to the geometry of the electrode lattice structures. Finally, plasma power does not track linearly with perimeter in these more complicated lattice structures.
- Open Access
- 25 May 2023
- Published by Springer Nature in Research Square
Analysis of the Effects of Complex Electrode Geometries on the Energy Deposition and Electric Field Measurements of Surface Dielectric Barrier Discharges
Surface Dielectric Barrier Discharges (SDBDs) have been gaining interest in recent years for numerous applications. One of the advantages of SDBDs is their scalability and flexibility of materials used, allowing larger electrodes than simple linear electrodes investigated in earlier works. This paper seeks to elucidate the properties of more complicated SDBD geometries utilizing differing repeated lattice structures. Voltage and current traces, optical emission spectroscopy, digital imaging, and numerical analysis are used to analyze the electrodes. Reduced electric fields obtained through optical emission spectroscopy and the total power deposited into the plasma are presented. The reduced electric field is not significantly affected by increasing applied voltage, but minor variations could be observed due to the geometry of the electrode lattice structures. Finally, it was observed that plasma power is not a simple linear relationship in these more complicated lattice structures. Smaller lattice structures were observed to have lower energy deposited per period.
- 25 May 2023
- Published by Springer Nature in Research Square
Open AccessAnalysis of the Effects of Complex Electrode Geometries on the Energy Deposition and Electric Field Measurements of Surface Dielectric Barrier Discharges
Surface Dielectric Barrier Discharges (SDBDs) have been gaining interest in recent years for numerous applications. One of the advantages of SDBDs is their scalability and flexibility of materials used, allowing larger electrodes than simple linear electrodes investigated in earlier works. This paper seeks to elucidate the properties of more complicated SDBD geometries utilizing differing repeated lattice structures. Voltage and current traces, optical emission spectroscopy, digital imaging, and numerical analysis are used to analyze the electrodes. Reduced electric fields obtained through optical emission spectroscopy and the total power deposited into the plasma are presented. The reduced electric field is not significantly affected by increasing applied voltage, but minor variations could be observed due to the geometry of the electrode lattice structures. Finally, it was observed that plasma power is not a simple linear relationship in these more complicated lattice structures. Smaller lattice structures were observed to have lower energy deposited per period.
- 1 June 2022
- Published by SAGE Publications in Soft Robotics
- Vol. 9 (3) , 542-551
Paper-Based Robotics with Stackable Pneumatic Actuators
This work presents a unique approach to the design, fabrication, and characterization of paper-based origami robotic systems consisting of stackable pneumatic actuators. These paper-based actuators (PBAs) use materials with high elastic modulus-to-mass ratios, accordion-like structures, and direct coupling with pneumatic pressure for extension and bending. The study contributes to the scientific and engineering understanding of foldable components under applied pneumatic pressure by constructing stretchable and flexible structures with intrinsically nonstretchable materials. Experiments showed that a PBA possesses a power-to-mass ratio greater than 80 W/kg, which is more than four times that of human muscle. This work also illustrates the stackability and functionality of PBAs by two prototypes: a parallel manipulator and a legged locomotor. The manipulator consisting of an array of PBAs can bend in a specific direction with the corresponding actuator inflated. In addition, the stacked actuators in the manipulator can rotate in opposite directions to compensate for relative rotation at the ends of each actuator to work in parallel and manipulate the platform. The locomotor rotates the PBAs to apply and release contact between the feet and the ground. Furthermore, a numerical model developed in this work predicts the mechanical performance of these inflatable actuators as a function of dimensional specifications and folding patterns. Overall, we use stacked origami actuators to implement functionalities of manipulation, gripping, and locomotion as conventional robotic systems. Future origami robots made of paper-like materials may be suitable for single use in contaminated or unstructured environments or low-cost educational materials.
- 1 June 2022
- Published by SAGE Publications in Soft Robotics
- Vol. 9 (3) , 542-551
Paper-Based Robotics with Stackable Pneumatic Actuators
This work presents a unique approach to the design, fabrication, and characterization of paper-based origami robotic systems consisting of stackable pneumatic actuators. These paper-based actuators (PBAs) use materials with high elastic modulus-to-mass ratios, accordion-like structures, and direct coupling with pneumatic pressure for extension and bending. The study contributes to the scientific and engineering understanding of foldable components under applied pneumatic pressure by constructing stretchable and flexible structures with intrinsically nonstretchable materials. Experiments showed that a PBA possesses a power-to-mass ratio greater than 80 W/kg, which is more than four times that of human muscle. This work also illustrates the stackability and functionality of PBAs by two prototypes: a parallel manipulator and a legged locomotor. The manipulator consisting of an array of PBAs can bend in a specific direction with the corresponding actuator inflated. In addition, the stacked actuators in the manipulator can rotate in opposite directions to compensate for relative rotation at the ends of each actuator to work in parallel and manipulate the platform. The locomotor rotates the PBAs to apply and release contact between the feet and the ground. Furthermore, a numerical model developed in this work predicts the mechanical performance of these inflatable actuators as a function of dimensional specifications and folding patterns. Overall, we use stacked origami actuators to implement functionalities of manipulation, gripping, and locomotion as conventional robotic systems. Future origami robots made of paper-like materials may be suitable for single use in contaminated or unstructured environments or low-cost educational materials.
- Open Access
- 16 July 2021
- Published by ASME International
Soft Robots With Reconfigurable and Deactivatable Endoskeloton
Soft robots have been attracting great attention for high flexibility and versatility. One of the most significant shortcomings of soft robots is their low bending stiffness due to the intrinsic soft nature of their body. Therefore, as their aspect ratio increases (e.g. long and slender), they have difficulty in maintaining their shape due to gravity. To address this inherent
- 16 July 2021
- Published by ASME International
Open AccessSoft Robots With Reconfigurable and Deactivatable Endoskeloton
Soft robots have been attracting great attention for high flexibility and versatility. One of the most significant shortcomings of soft robots is their low bending stiffness due to the intrinsic soft nature of their body. Therefore, as their aspect ratio increases (e.g. long and slender), they have difficulty in maintaining their shape due to gravity. To address this inherent
- Open Access
- 16 July 2021
- Published by ASME International
Experimental Investigation and Modeling of Three-Phase, Conductive, Cellulose-Based Paper
Paper-based electronics are emerging as lightweight, recyclable, and low-cost options for advanced mechanical, chemical, and electrical sensing. As one potential application of papertronics, paper-based skins may be capable of sensing touch, temperature, pressure, and humidity on synthetic or natural surfaces. Current paper-based skins mostly use paper as passive platforms to
- 16 July 2021
- Published by ASME International
Open AccessExperimental Investigation and Modeling of Three-Phase, Conductive, Cellulose-Based Paper
Paper-based electronics are emerging as lightweight, recyclable, and low-cost options for advanced mechanical, chemical, and electrical sensing. As one potential application of papertronics, paper-based skins may be capable of sensing touch, temperature, pressure, and humidity on synthetic or natural surfaces. Current paper-based skins mostly use paper as passive platforms to
- Open Access
- 16 July 2021
- Published by ASME International
Paper-Based Robotics With Stackable Pneumatic Actuators
Paper continues to receive attention as a material for electronics and robotics due to its low-cost, recyclability, and foldability. In recent years, there has been an increasing amount of literature on origami/kirigami robots made of paper-like materials, which are thin, foldable, and intrinsically unstretchable. Although the word “origami/kirigami” means folding/cutting paper,
- 16 July 2021
- Published by ASME International
Open AccessPaper-Based Robotics With Stackable Pneumatic Actuators
Paper continues to receive attention as a material for electronics and robotics due to its low-cost, recyclability, and foldability. In recent years, there has been an increasing amount of literature on origami/kirigami robots made of paper-like materials, which are thin, foldable, and intrinsically unstretchable. Although the word “origami/kirigami” means folding/cutting paper,