Melissa J. Cox

Melissa J. Cox

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

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Previous Organizations / Institutes

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Melissa J. Cox has a total of 74 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Understanding Age Verification Practices: A Qualitative Study to Inform Community-Level Interventions

    by Wynne Ebner, McKenna Roudebush, Adriana Gaona, Samantha Luu, Melissa J. Cox

    Underage alcohol use remains a significant public health problem in the United States. Access to alcohol is a key driver of underage drinking, and youth often obtain alcohol by using false identification (fake IDs). While enforcement of minimum drinking age laws is an evidence-based strategy to reduce underage drinking, little systematic examination of age verification practices exists. To address this need, we conducted key informant interviews ( N = 8) with staff and owners of alcohol retailers as well as law enforcement officers in a Southeastern U.S. college town between October 2023 and April 2024. Participants were queried on factors influencing age verification practices. We coded and thematically analyzed the data using an iterative, multistep process. Results revealed three primary themes: (a) ID verification practices varied widely among retail participants; (b) facilitators of effective ID checks included staff training, access to advanced technology, and workplace support, while barriers included resource limitations, increasingly sophisticated fake IDs, and challenging interactions with patrons; and (c) participants considered both the legal and public health implications of selling alcohol to underage individuals. These findings suggest a need for tailored, equity-centered practice strategies, such as updated training programs and equitable enforcement policies, to address the evolving challenges of fake ID detection. Future research should continue exploring diverse perspectives from those involved in ID verification, focusing on identifying the challenges and strengths of implementing community-level policies. These insights can inform interventions to strengthen age verification practices, reduce underage alcohol access, and minimize related harms.

  • Open Access

    A pilot randomized controlled trial assessing the feasibility and preliminary effects of a text message intervention to promote secure storage and disposal of prescription opioids

    by Kathleen L. Egan, Melissa J. Cox, Donald W. Helme, J. Todd Jackson, Lyle D. Paukner, David M. Kline, Alice R. Richman

  • Open Access

    Text Message Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids to Prevent Diversion and Misuse: Protocol for a Randomized Controlled Trial

    by Kathleen L Egan, Melissa J Cox, Donald W Helme, J Todd Jackson, Alice R Richman

    Background: Nonmedical use of prescription opioids remains a critical public health issue; 8.5 million people in the United States misused opioids in 2022. Most people obtain prescription opioids for misuse from family or friends. Thus, facilitating secure storage and disposal of opioid medications during and after treatment is needed to prevent medication diversion and subsequent misuse. Objective: The primary objective of this study is to test the feasibility and efficacy of a novel intervention that uses a persuasive, informational SMS text message reminder system to enhance the impact of secure storage and disposal of unused opioid medications. We hypothesize that the SMS text message intervention will increase secure storage during treatment and disposal of prescription opioids after treatment. Methods: We will use a 2-arm randomized controlled trial to test the intervention for feasibility and efficacy. Participants (aged 18+ years who have received an opioid prescription in the past 2 weeks) will be randomly assigned to either receive the SMS text message intervention or standard-of-care educational materials. Participants in the intervention will receive 4 SMS text messages related to secure storage and 3 messages related to disposal. All participants will complete baseline, midpoint (day 25), and postintervention (day 45) evaluation surveys. We will test whether receipt of the intervention is associated with two primary outcomes, which are (1) secure storage of prescription opioid medication (locked vs unlocked) and (2) disposal of unused prescription opioid medication (disposed vs not disposed). We will use multiple logistic regression to test the main hypotheses that the intervention will be positively associated with secure storage (locked vs unlocked) and disposal (yes vs no) behaviors, which will allow us to control for demographic variables known to influence the outcomes. This protocol represents the entire structure of the randomized controlled trial. Results: Recruitment for the randomized controlled trial was launched in April 2024, and data collection was completed in December 2024. The final sample size is 484. Data analyses for the main hypothesis will be completed by May 2025, and the main hypothesis manuscript will be submitted for publication by May 2025. Conclusions: Results from this study will indicate whether a text message reminder system can increase secure storage and disposal behaviors for individuals who receive opioid medication. This type of intervention has the potential to be integrated into currently used health care delivery systems, such as prescription pickup reminders at pharmacies. Thus, the intervention is scalable across systems of care, thus expanding the reach of secure storage and disposal programs to prevent prescription opioid misuse. Trial Registration: ClinicalTrials.gov NCT05503186; https://clinicaltrials.gov/study/NCT05503186 International Registered Report Identifier (IRRID): DERR1-10.2196/60332


  • A systematic review of the associations between protective behavioral strategies and heavy alcohol consumption and consequences among young adults.

    by Melissa J. Cox, Angelo M. DiBello, Emily P. Jones, Jordan Gette, Avanti Godbole, Loren Barcenas, McKenna Roudebush, Josh Simensky, Lindsay Mancini, Aashna Gheewalla, et al.

    We systematically reviewed the literature to assess the association between use of alcohol protective behavioral strategies (PBS) and young adult heavy drinking and alcohol-related consequences. We followed the preferred reporting items for systematic review and meta-analysis guidelines to select and review research studies that were comprised of a sample of young adults ages 18-26, included PBS derived from one of 10 validated scales as an independent variable, measured heavy alcohol use or alcohol consequences as the dependent variable, and tested the direct association between the two. Studies were gathered via PubMed, Scopus, Cumulative Index to Nursing and Allied Health Literature, APA PsycInfo, and Global Health. All identified study records underwent a two-step screening process and risk of bias assessment. Data were extracted from 94 studies that met inclusion criteria; 16 studies (17%) examined associations with heavy alcohol use and 91 studies (97%) tested effects of PBS on alcohol consequences. All studies that measured a total effect of PBS use (summations across all strategies) found significant negative associations with heavy alcohol use and 91% were negatively associated with alcohol consequences. Most studies that examined subscales of PBS found at least one significant, negative relation with heavy alcohol use (73%) and alcohol-related consequences (78%), though effects varied across type of subscale (e.g., manner of drinking). Our results support the use of PBS to address heavy alcohol consumption and related harms among young adults. Opportunities for refinement of current PBS in preventive interventions are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


  • Open Access

    Text Message Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids to Prevent Diversion and Misuse: Protocol for a Randomized Controlled Trial (Preprint)

    by Kathleen L Egan, Melissa J Cox, Donald W Helme, J Todd Jackson, Alice R Richman

    BACKGROUND Nonmedical use of prescription opioids remains a critical public health issue; 8.5 million people in the United States misused opioids in 2022. Most people obtain prescription opioids for misuse from family or friends. Thus, facilitating secure storage and disposal of opioid medications during and after treatment is needed to prevent medication diversion and subsequent misuse. OBJECTIVE The primary objective of this study is to test the feasibility and efficacy of a novel intervention that uses a persuasive, informational SMS text message reminder system to enhance the impact of secure storage and disposal of unused opioid medications. We hypothesize that the SMS text message intervention will increase secure storage during treatment and disposal of prescription opioids after treatment. METHODS We will use a 2-arm randomized controlled trial to test the intervention for feasibility and efficacy. Participants (aged 18+ years who have received an opioid prescription in the past 2 weeks) will be randomly assigned to either receive the SMS text message intervention or standard-of-care educational materials. Participants in the intervention will receive 4 SMS text messages related to secure storage and 3 messages related to disposal. All participants will complete baseline, midpoint (day 25), and postintervention (day 45) evaluation surveys. We will test whether receipt of the intervention is associated with two primary outcomes, which are (1) secure storage of prescription opioid medication (locked vs unlocked) and (2) disposal of unused prescription opioid medication (disposed vs not disposed). We will use multiple logistic regression to test the main hypotheses that the intervention will be positively associated with secure storage (locked vs unlocked) and disposal (yes vs no) behaviors, which will allow us to control for demographic variables known to influence the outcomes. This protocol represents the entire structure of the randomized controlled trial. RESULTS Recruitment for the randomized controlled trial was launched in April 2024, and data collection was completed in December 2024. The final sample size is 484. Data analyses for the main hypothesis will be completed by May 2025, and the main hypothesis manuscript will be submitted for publication by May 2025. CONCLUSIONS Results from this study will indicate whether a text message reminder system can increase secure storage and disposal behaviors for individuals who receive opioid medication. This type of intervention has the potential to be integrated into currently used health care delivery systems, such as prescription pickup reminders at pharmacies. Thus, the intervention is scalable across systems of care, thus expanding the reach of secure storage and disposal programs to prevent prescription opioid misuse. CLINICALTRIAL ClinicalTrials.gov NCT05503186; https://clinicaltrials.gov/study/NCT05503186 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/60332

  • The impact of “pinkwashed” alcohol advertisements on attitudes and beliefs: A randomized experiment with US adults

    by Marissa G. Hall, Cristina J.Y. Lee, David H. Jernigan, Phoebe Ruggles, Melissa Cox, Callie Whitesell, Anna H. Grummon


  • Alcohol protective behavioral strategies for young adults: a content analysis across drinking contexts and gender

    by McKenna Roudebush, Avanti Godbole, Lois Johnson, Kathleen L. Egan, Melissa J. Cox

    Background: Protective behavioral strategies (PBS) are specific harm reduction behaviors which mitigate alcohol-related consequences among young adults. Prior work indicates PBS utilization varies according to drinking context and gender, suggesting a need for further research assessing whether young adults employ unidentified PBS according to such factors.Objectives: This study examined alcohol PBS young adults suggest using across drinking contexts and gender to inform alcohol-related harm reduction interventions.Methods: An online survey with 514 young adult heavy drinkers (n = 269 female, Mage = 22.36 years) assessed PBS use generally, and across 12 physical and social contexts. We utilized qualitative content analysis methods to code and derive themes from open-ended responses from a prompt asking participants to state additional PBS used per context. The frequency of each theme's appearance was calculated across the overall sample, by gender, and within each context.Results: PBS endorsement varied across context and gender within each theme. Young adults who reported PBS use most frequently endorsed utilizing strategies related to drink content (18.30%), social support (12.36%), and engaging in other activities (10.34%). Participants infrequently endorsed strategies related to awareness of time (0.23%), standards of behavior (0.78%) and avoiding environments (0.87%).Conclusions: Young adults endorse utilizing additional PBS in varying frequency according to drinking context and gender. Given PBS are often a key component of alcohol harm reduction interventions, monitoring trends in young adult PBS use is crucial to ensure continued relevance and efficacy of such interventions to minimize harms associated with young adult heavy alcohol use.